Localized cutaneous argyria: Report of two patients and literature review
General Material Designation
[Article]
First Statement of Responsibility
Beutler, Bryce David; Lee, Robert A; Cohen, Philip R
SUMMARY OR ABSTRACT
Text of Note
BackgroundLocalized cutaneous argyria is a rare skin condition caused by direct contact with silver or silver particles. It presents as asymptomatic gray or blue-gray macules that appear similar to blue nevi. Histologic features include brown-colored or black-colored silver granules in the basement membrane and dermis, most commonly surrounding eccrine glands, elastic fibers, and collagen fibrils. The condition is most frequently observed in individuals who are regularly exposed to small silver particles, such as silversmiths and welders. However, localized cutaneous argyria has also been associated with acupuncture needles, silver earrings, and topical medications containing silver nitrate. Although the condition is benign, patients who are concerned about the cosmetic features of localized cutaneous argyria may benefit from laser therapy.
SET
Date of Publication
2016
Title
Dermatology Online Journal
Volume Number
22/11
PERSONAL NAME - PRIMARY RESPONSIBILITY
Entry Element
Beutler, Bryce David; Lee, Robert A; Cohen, Philip R