Eungdamrong, John; Boyd, Kevin P; Meehan, Shane A; Latkowski, Jo-Ann
SUMMARY OR ABSTRACT
Text of Note
A 35-year-old man initially was referred for management of recalcitrant urticaria. Owing to his long history of arthritis and sensorineural hearing loss, genetic testing was performed. The test showed a D305N heterozygous mutation in the NLRP3 gene, which is consistent with the diagnosis of Muckle-Wells syndrome. We discussed the rationales behind the use of the interleukin-1 antagonist anakinra in this autoinflammatory disorder.
SET
Date of Publication
2013
Title
Dermatology Online Journal
Volume Number
19/12
PERSONAL NAME - PRIMARY RESPONSIBILITY
Entry Element
Eungdamrong, John; Boyd, Kevin P; Meehan, Shane A; Latkowski, Jo-Ann