A case illustrating successful eradication of recurrent, aggressive basal cell carcinoma located in a scar with vismodegib
General Material Designation
[Article]
First Statement of Responsibility
Lucero, Olivia M; Fitzmaurice, Sarah; Thompson, Curtis; Leitenberge, Justin
SUMMARY OR ABSTRACT
Text of Note
Vismodegib is a small molecule inhibitor of the Hedgehog signaling pathway that has shown efficacy in the control of locally advanced or metastatic basal cell carcinoma, although proof of its effectiveness in the elimination of aggressive tumors is lacking. We report a case and provide complete histological evidence of a 69-year-old gentleman who presented with a recurrent, infiltrative, and sclerosing (morpheiform) basal cell carcinoma on his left upper lip that was entirely eradicated with a three-month course of vismodegib 150 mg daily. Complete histologic clearance of a tumor in a recurrent, infiltrative, and sclerosing basal cell carcinoma with vismodegib is uncommon.
SET
Date of Publication
2018
Title
Dermatology Online Journal
Volume Number
24/2
PERSONAL NAME - PRIMARY RESPONSIBILITY
Entry Element
Lucero, Olivia M; Fitzmaurice, Sarah; Thompson, Curtis; Leitenberge, Justin