Prognostic Modeling in Desmoplastic Melanoma Using Different Cutpoints for the Proportion of Desmoplasia
General Material Designation
[Article]
First Statement of Responsibility
Ming, Michael E; Nwaneshiudu, Adaobi I; Xu, Xiao-Wei; Karakousis, Giorgos C; Elder, David E; Elenitsas, Rosalie
SUMMARY OR ABSTRACT
Text of Note
Currently, desmoplastic melanomas are commonly divided into "pure" desmoplastic melanoma (at least 90% desmoplasia histologically) and "mixed" (<90%), with pure having a better prognosis, but our understanding of the relationship between percent desmoplasia and prognosis is incomplete. We sought to determine whether a more refined grading system that examined extent of desmoplasia by percent in 10% increments would be a better prognostic model. We also sought to determine the optimal cutpoint for percent desmoplasia if a single cutpoint were used.
SET
Date of Publication
2016
Title
Dermatology Online Journal
Volume Number
22/9
PERSONAL NAME - PRIMARY RESPONSIBILITY
Entry Element
Ming, Michael E; Nwaneshiudu, Adaobi I; Xu, Xiao-Wei; Karakousis, Giorgos C; Elder, David E; Elenitsas, Rosalie