عنوان

A case of Graham-Little-Piccardi-Lasseur syndrome

Number

LA7gj157xg

.Language of Text, Soundtrack etc

انگلیسی

Title Proper

A case of Graham-Little-Piccardi-Lasseur syndrome

General Material Designation

[Article]

First Statement of Responsibility

Yorulmaz, Ahu; Artuz, Ferda; Er, Olcay; Guresci, Servet

Text of Note

Graham-Little-Piccardi-Lasseur Syndrome (GLPLS) is a variant of lichen planopilaris, which is characterized by progressive cicatricial alopecia of scalp, non-cicatricial alopecia of axillae and pubic regions, and keratosis pilaris-like follicular papules over trunk and extremities. GLPLS is a disease of unknown etiology. However, recent reports support a central role for a T-cell-mediated immune response in the pathogenesis of GLPLS. Besides, although GLPLS is believed to occur sporadically, a genetic predisposition also has been implicated in the pathogenesis. On the other hand, GLPLS typically affects middle-aged women, particularly of the postmenopausal age group. A diagnosis of GLPLS is generally apparent with the presence of characteristic findings in a postmenopausal woman. Herein, we report a case of GLPLS in a 75-year-old woman with the typical triad of alopecia of the scalp, non-cicatricial alopecia of axillae and pubis, and a follicular keratotic eruption on the trunk.

Date of Publication

2015

Title

Dermatology Online Journal

Volume Number

21/6

Entry Element

Yorulmaz, Ahu; Artuz, Ferda; Er, Olcay; Guresci, Servet

Electronic name

[Article]

275578

a

Y