عنوان

Sabra dermatitis: combined features of delayed hypersensitivity and foreign body reaction to implanted glochidia

Number

LA2157f9g0

.Language of Text, Soundtrack etc

انگلیسی

Title Proper

Sabra dermatitis: combined features of delayed hypersensitivity and foreign body reaction to implanted glochidia

General Material Designation

[Article]

First Statement of Responsibility

Magro, Cynthia; Lipner, Shari

Text of Note

A striking dermatitis referred to by its colloquial designation of sabra dermatitis is associated with glochidia inoculation from the Opuntia cactus commonly known as the prickly pear. We report a 45-year-old woman who had an unexpected encounter with a cactus plant during a trip to Texas. She brushed up against the plant and was aware that she had been inoculated with several spines of the plant. Five days later she developed erythematous papules on the digits accompanied by swelling. The biopsy showed a very striking granulomatous reaction pattern within the dermis. There was a linear pattern of necrobiosis, likely representing a tract of inoculation injury palisaded by histiocytes including multinucleated forms. This necrobiotic tract demonstrated retained glochidia, each measuring roughly 40 to 70 microns in diameter. The nature of the inflammatory response is one that combines features of classic delayed hypersensitivity and an innate foreign body response. The glochidia are capable of eliciting a T cell mediated immune response; it is reasonable to assume that a Th1 cytokine signal is responsible for the unique pattern of inflammation including the secondary influx of neutrophils and relative lack of tissue eosinophilia.

Date of Publication

2020

Title

Dermatology Online Journal

Volume Number

26/4

Entry Element

Magro, Cynthia; Lipner, Shari

Electronic name

[Article]

275578

a

Y