The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders
General Material Designation
[Article]
First Statement of Responsibility
Saric-Bosanac, Suzana; Clark, Ashley K; Sivamani, Raja K; Shi, Vivian Y
SUMMARY OR ABSTRACT
Text of Note
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity. The pilosebaceous unit is a site for production and metabolism of a number of steroid hormones, including stress and sex hormones. This is an overview of the important role that the cutaneous HPA-like-axis plays in the pathogenesis and treatment of inflammatory pilosebaceous disorders, including acne, rosacea, seborrheic dermatitis, and hidradenitis suppurativa.
SET
Date of Publication
2020
Title
Dermatology Online Journal
Volume Number
26/2
PERSONAL NAME - PRIMARY RESPONSIBILITY
Entry Element
Saric-Bosanac, Suzana; Clark, Ashley K; Sivamani, Raja K; Shi, Vivian Y