عنوان

Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice:

Number

LA06t1n9d7

Title Proper

Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice:

General Material Designation

[Article]

First Statement of Responsibility

McGregor, Alyson J.Beauchamp, Gillian A.Wira, Charles R.Perman, Sarah M.Safdar, Basmah

Title Proper by Another Author

A Brief Narrative Review

Text of Note

The National Institutes of Health recently highlighted the significant role of sex as a biologicalvariable (SABV) in research design, outcome and reproducibility, mandating that this variable beaccounted for in all its funded research studies. This move has resulted in a rapidly increasing bodyof literature on SABV with important implications for changing the clinical practice of emergencymedicine (EM). Translation of this new knowledge to the bedside requires an understanding ofhow sex-based research will ultimately impact patient care. We use three case-based scenarios inacute myocardial infarction, acute ischemic stroke and important considerations in pharmacologictherapy administration to highlight available data on SABV in evidence-based research to providethe EM community with an important foundation for future integration of patient sex in the delivery ofemergency care as gaps in research are filled.

Date of Publication

2017

Title

UC Irvine

Electronic name

[Article]

277908

a

Y