Deep tissue monitoring enabled by wearable ultrasonic devices and machine learning
General Material Designation
[Thesis]
First Statement of Responsibility
Zhang, Zhuorui
Subsequent Statement of Responsibility
Xu, Sheng
.PUBLICATION, DISTRIBUTION, ETC
Date of Publication, Distribution, etc.
2019
DISSERTATION (THESIS) NOTE
Body granting the degree
Xu, Sheng
Text preceding or following the note
2019
SUMMARY OR ABSTRACT
Text of Note
Benefiting from the development of wearable electronic devices, various physiological signals, such as body temperature, hydration, glucose/lactate levels, and local field potentials, can already be monitored continuously and noninvasively. Among all physiological signals, those deeply beneath the skin, including central blood pressure, blood flow and activities of major organs, are particularly important since they are directly related to the subject's life-sustaining capability. However, there is a lack of devices that could give continuous and reliable readings of these vital signs. Their common limitations can be summarized as: limited penetration depth and operator dependence. Herein, we use human carotid artery as an example and demonstrate wearable ultrasonic devices supported by control electronics and adaptive algorithms to achieve automatic deep tissue monitoring. To eliminate the operator dependence of ultrasound technology, machine learning-based algorithms were developed addressing the blood vessel positioning and wall tracking tasks.