11.3 Theoretical Background and Conceptual Framework of Critical Transitions
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Includes bibliographical references.
CONTENTS NOTE
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Intro; Foreword; Preface; Contents; Creating a Better World with Science and Technology; 1 Further Pushing the Boundaries of Possibility; 1.1 What Has Allowed Merck to Thrive for 350 Years?; 1.2 A Vibrant Science and Technology Company; 1.3 Curious Minds Dedicated to Human Progress; 1.4 Pushing the Boundaries of Possibility; 1.5 Making Curiosity Thrive; 1.6 Helping Tackle Global Challenges; 1.7 Let's Unleash the Potential of Science and Technology; 2 Building a Better World with Science and Technology: Curious Future Insight; Acknowledgements; 3 Future Insight Prize-From Dream to Reality
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10 Out of Curiosity from Blue Sky Research to Medical Innovation10.1 Introduction; 10.2 The Resolution-Revolution; 10.3 Pushing the Dimension Frontier: From Temporal to Spatial to Distributions; 10.4 From Chemistry to Biology and Back Again; 10.5 Chemistry of the Biological World; 10.6 Understanding Diseases-The Prerequisite for Translation into Clinical Medicine; 10.7 Medicine-Quo Vadis?; 10.8 AI and Robotics Will Transform Medicine; 10.9 Interdisciplinarity; References; 11 From Diagnosing Diseases to Predicting Diseases; 11.1 Introduction; 11.2 Diseases as Perturbations of Networks
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7 The Changing Landscape for New Drug Development: Medical Countermeasures (MCMs) as a Case Study7.1 Introduction; 7.2 Early Evolution of a New R & D Sub-sector [4]; 7.3 Impact Factors for Sector Building in the Twenty-Teens [7]; 7.3.1 Facilitated Regulatory Pathways (FRPs); 7.3.2 Prioritization and Access to FRPs; 7.3.3 Emerging Sponsors and Paradigm Shift; 7.3.4 Patient-Focused Drug Development (PFDD); 7.4 What Happened to the MCM Sector from 2008 to 2016? [9]; 7.5 Key Factors for the Future: Proving and Paying for Value [10]; 7.6 Global NAS Launches 2013-2017: Trends and Implications [11]
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7.7 What the MCM Experience Portends for Drug Development in 2020 and BeyondReferences; 8 In the Face of Global Health Challenges-Let's Redefine Innovation; References; 9 Neglected Parasitic Infections and the Syndemic Anemia Vaccines for Africa; 9.1 Introduction; 9.2 Rationale for Linking Malaria with Helminth Control; 9.3 Syndemic Anemia Vaccines; 9.3.1 Malaria Vaccine; 9.3.2 Human Hookworm Vaccine; 9.3.3 Schistosomiasis Vaccine; 9.4 Maternal-Child Target Product Profiles of an Anemia Vaccine; 9.5 New Public-Private Strategic Alliances; 9.6 Next Steps and Future Directions; References
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Acknowledgements4 Curious2018-Future Insight; 4.1 Sometimes no Strategy Is the Best Approach; 4.2 Small Questions Are Good Too; 4.3 Humans, Microbes, and Medicine; 4.3.1 Society 5.0; 4.3.2 The Final Frontier; 5 The Darmstadt Science Declaration-Make Science not War; Science and Technology at Its Best-Examples from Curious2018 Future Insight Conference Keynote Speakers; 6 Integrating Modern Immunology into Medicine; 6.1 Introduction; 6.2 New Paradigms; 6.3 Technological Advances; 6.3.1 'Deep' Phenotyping of White Blood Cells; 6.3.2 B and T Cell Responses; 6.4 Conclusion; References
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SUMMARY OR ABSTRACT
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This book expands the debate on the future of science and technology at the Curious2018 - Future Insight Conference, held on the occasion of Merck's 350-year anniversary. In the respective chapters, some of the world's top scientists, managers and entrepreneurs explore breakthrough technologies and how they can be applied to make a better world for humanity. Divided into three parts, the book begins with an introduction to the vision of the conference and to the importance of curiosity for innovation, while also exploring the latest scientific developments that are shaping the future of healthcare, medicine, the life and material sciences, digitalization and new ways of working together. In the second part, particular attention is paid to new therapies and diagnostics; here, readers will learn how synthetic biology and chemistry are being used to solve problems that are essential to the future of humanity. The role of in-silico research is also discussed. In the final part of the book, readers will find some thoughts on ethical principles guiding our application of science and technology to create a bright future for humanity. Given its interdisciplinary appeal, the book will inspire curiosity in a wide readership, from scholars and researchers to professionals with an interest in exploring the future of science and technology, solving the problems of today, and paving the way for a better tomorrow. Chapters 1, 2, 3 and 17 are available open access under a Creative Commons Attribution-NonCommercial 4.0 International License via link.springer.com. Book includes a foreword from J. Craig Venter.
ACQUISITION INFORMATION NOTE
Source for Acquisition/Subscription Address
Springer Nature
Stock Number
com.springer.onix.9783030160616
OTHER EDITION IN ANOTHER MEDIUM
Title
Curious2018 : Future Insights in Science and Technology.