Intraocular and intracranial pressure gradient in glaucoma /
General Material Designation
[Book]
First Statement of Responsibility
Ningli Wang, editor.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Singapore :
Name of Publisher, Distributor, etc.
Springer,
Date of Publication, Distribution, etc.
2019.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource
SERIES
Series Title
Advances in visual science and eye diseases ;
Volume Designation
volume 1
CONTENTS NOTE
Text of Note
Intro; Preface; Contents; Contributors; Part I: Review of the Study of Trans-laminar Cribrosa Pressure Difference; 1: Road Map for the Pathogenesis of Glaucomatous Optic Neuropathy; References; 2: Time to Eliminate "Normal Tension" in Primary Open-Angle Glaucoma; 2.1 Introduction; 2.2 Origin of Normal-Tension Glaucoma; 2.3 Pathogenesis of Primary Open-Angle Glaucoma; 2.4 Genetics of POAG; 2.5 Is NTG Clinically Distinguishable from POAG?; 2.6 Conclusion; References; 3: Intracranial and Intraocular Pressure-Related Diseases; 3.1 Anatomy; 3.2 Epidemiology
Text of Note
3.3 IOP: A Dilemma in Glaucoma Diagnosis and Treatment3.4 Cerebrospinal Fluid Pressure: The New Dangerous Factor; 3.5 Trans-laminar Cribrosa Pressure Difference (TLPD): The Pathogenesis for Glaucoma?; 3.6 Mechanisms and Clinical Implications; 3.7 Conclusion; References; 4: Conciliation of Discrepancy of Hypertensive Glaucoma and Normal-Tension Glaucoma Through Intraocular-Intracranial Pressure Gradient; 4.1 The Historical Evolution of the Definition of Glaucoma; 4.2 The Transitions of the Definition of Primary Glaucoma in Recent Guidelines and Expert Consensuses
Text of Note
4.2.1 Transitions of the Definition of Primary Open-Angle Glaucoma (POAG)4.2.1.1 POAG Definition in the Expert Consensuses in China; 4.2.1.2 POAG Definition by the American Academy of Ophthalmology (AAO); 4.2.1.3 Contrast of POAG Definitions Between China and America; 4.2.2 Transitions of the Definition of Primary Angle-Closure Glaucoma (PACG); 4.2.2.1 The Classification System by the International Society of Geographical and Epidemiological Ophthalmology (ISGEO); 4.2.2.2 PACG Definition in China; 4.2.2.3 Contrast of PACG Definitions and Classifications Between China and America
Text of Note
4.3 New Hypotheses and Theories About the Relationship Between Pressure and Glaucoma4.3.1 "Safe IOP Hypothesis"; 4.3.2 "Ocular-Cranial Pressure Gradient Theory"; 4.4 Summary; References; 5: Primary Open-Angle Glaucoma, Trans-Lamina Cribrosa Pressure Difference, and Central Nerve System; 5.1 The Relationship Between POAG and CNS Diseases; 5.2 The Relationship Between POAG and TLPD; 5.3 DBA/2 Mouse Model of Glaucoma; 5.3.1 Obstruction of Axoplasmic Transport in Glaucoma Was Developed from the Proximal to the Distal Axon
Text of Note
5.3.2 Obstruction of Distal Axonal Transport in Glaucoma Owns Characteristics of Age-Dependent and Retinal Localization5.3.3 The Axonal Structure of RGC Cells in Glaucoma Is Still Preserved After the Obstruction of Axonal Transport; 5.4 The Visual Pathway Damage Induced by POAG; 5.4.1 The Damage of the Anterior Visual Pathway of POAG; 5.4.2 The Damage of Posterior Visual Pathway in POAG; 5.4.3 Other Glaucomatous Damage in CNS; 5.5 Mechanism of Action (MOA) Study of CNS Damage in Glaucoma; 5.6 Summary; References; 6: The Role of CSFP in Glaucoma: A View in Retrospect; References
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SUMMARY OR ABSTRACT
Text of Note
This book focuses on the characteristic of glaucomatous optic neuropathy and its relationship with cerebrospinal fluid (CSF) pressure. It also explores the potential novel methods to manage glaucoma by adjusting CSF pressure. This book covers several interesting topics such as why normal tension glaucoma (NTG) patients still develops into glaucoma without high intraocular pressure (IOP); and whether there are factors other than IOP contributing to the pathogenesis of NTG why the role of IOP in the pathogenesis of POAG becomes vague and controversial. This book contains over 40 chapters, including numerous images from clinical patients and experiments on gross anatomy, pathological tissue, and immunohistochemistry, electronic speculum etc. The ophthalmologists and researchers can also benefit from the clinical cases. We hope this book serves as a clinical guidance with practical significant for the understanding, prevention and diagnosis of glaucoma.