عنوان

Chromosome translocation /

(Number (ISBN

9789811305931

(Number (ISBN

9811305935

Erroneous ISBN

9789811305924

Erroneous ISBN

9811305927

Title Proper

Chromosome translocation /

General Material Designation

[Book]

First Statement of Responsibility

Yu Zhang, editor.

Place of Publication, Distribution, etc.

Singapore :

Name of Publisher, Distributor, etc.

Springer,

Date of Publication, Distribution, etc.

[2018]

Date of Publication, Distribution, etc.

©2018

Specific Material Designation and Extent of Item

1 online resource (v, 168 pages) :

Other Physical Details

illustrations (some color)

Series Title

Advances in experimental medicine and biology,

Volume Designation

volume 1044

ISSN of Series

2214-8019 ;

Text of Note

Includes bibliographical references.

Text of Note

Historical and clinical perspectives on chromosomal translocations / Ellen S. Wilch, Cynthia C. Morton -- Induction of chromosomal translocations with CRISPR-Cas9 and other nucleases: understanding the repair mechanisms that give rise to translocations / Erika Brunet, Maria Jasin -- Dynamics of double-strand breaks: implications for the formation of chromosome translocations / Henrike Johanna Gothe, Vera Minneker, Vassilis Roukos -- The CRISPR/Cas9 system as a tool to engineer chromosomal translocation in vivo / Taek-Chin Cheong, Rafael B. Blasco, Roberto Chiarle -- Generation of genomic alteration from cytidine deamination / Xiaojing Liu, Fei-Long Meng -- The role for the DSB response pathway in regulating chromosome translocations / Rajib Ghosh, Debamitra Das, Sonia Franco -- Telomeres and chromosomal translocations / Duncan M. Baird, Eric A. Hendrickson -- 3D genome organization influences the chromosome translocation pattern / Rachel Patton McCord, Adayabalam Balajee -- The role of chromosome deletions in human cancers / Mei Chen, Yi Yang, Yu Liu, Chong Chen -- Processing-challenges generated by clusters of DNA double-strand breaks underpin increased effectiveness of high-LET radiation and chromothripsis / Emil Mladenov, Janapriya Saha, George Iliakis.

0

Text of Note

"This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases. The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation"--Publisher's description.

Source for Acquisition/Subscription Address

Springer Nature

Stock Number

com.springer.onix.9789811305931

Title

Chromosome translocation.

International Standard Book Number

9789811305924

Translocation (Genetics)

Translocation, Genetic-- physiology.

SCIENCE-- Life Sciences-- Biochemistry.

Translocation (Genetics)

MFN

SCI-- 007000

Number

Edition

Class number

Class number

Zhang, Yu

Date of Transaction

20200823223933.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y