عنوان

Dengue and Zika :

(Number (ISBN

9789811087271

(Number (ISBN

981108727X

Erroneous ISBN

9789811087264

Erroneous ISBN

9811087261

Title Proper

Dengue and Zika :

General Material Designation

[Book]

Other Title Information

control and antiviral treatment strategies /

First Statement of Responsibility

Rolf Hilgenfeld, Subhash G. Vasudevan, editors.

Place of Publication, Distribution, etc.

Singapore :

Name of Publisher, Distributor, etc.

Springer,

Date of Publication, Distribution, etc.

[2018]

Date of Publication, Distribution, etc.

©2018

Specific Material Designation and Extent of Item

1 online resource (xiii, 375 pages) :

Other Physical Details

illustrations (chiefly color)

Series Title

Advances in experimental medicine and biology,

Volume Designation

volume 1062

ISSN of Series

2214-8019 ;

Text of Note

Includes bibliographical references and index.

Text of Note

Arboviruses on the rise -- Historical perspective of arboviruses in Mozambique and its implication for current and future epidemics -- Reliable serological testing for the diagnosis of emerging infectious diseases -- Flaviviral RNA structures and their role in replication and immunity -- The molecular specificity of the human antibody response to dengue virus infections -- Structures of Zika virus E & NS1: relations with virus infection and host immune responses -- Plugging the leak -- is dengue a case of aseptic shock with NS1 at its center -- Entry & NS1 as drug targets -- The dengue virus replication complex: from RNA replication to protein-protein interactions to evasion of innate immunity -- Crystal structure of Zika virus NS2B-NS3 protease -- The transactions of NS3 and NS5 in Dengue viral RNA replication -- Establishment and application of flavivirus replicons -- Strategies towards protease inhibitors for emerging flaviviruses -- Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent RNA polymerase from fragment screening and structure-guided design -- Nuclear cytoplasmic trafficking of dengue non-structural protein 5 as a target for antivirals -- Animal models for dengue and Zika vaccine development -- Understanding the human T cell response to dengue virus -- Regulation and function of NK and T cells during dengue virus infection and vaccination -- Structural insights into the broad-spectrum antiviral target Endoplasmic Reticulum alpha glucosidase II -- Mechanisms of antiviral activity of iminosugars against dengue virus -- Countering Zika virus: the USAMRIID response -- Dengue antiviral development: a continuing journey -- An industry perspective on dengue drug discovery and development -- The use of wolbachia by the Eliminate Dengue program to interrupt transmission of Aedes aegypti transmitted viruses -- Seroepidemiological studies of arboviruses in Africa.

0

Text of Note

"This contributed volume contains 25 chapters from leading international scientists working on Dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the "salt in the soup" of this book."--

Source for Acquisition/Subscription Address

Springer Nature

Stock Number

com.springer.onix.9789811087271

Title

Dengue and Zika.

International Standard Book Number

9789811087264

Dengue, Congresses.

Zika virus infection, Congresses.

Aedes.

Dengue Virus.

Dengue.

Zika Virus Infection.

Zika Virus.

Dengue.

HEALTH & FITNESS-- Diseases-- General.

MEDICAL-- Clinical Medicine.

MEDICAL-- Diseases.

MEDICAL-- Evidence-Based Medicine.

MEDICAL-- Internal Medicine.

Zika virus infection.

HEA-- 039000

MED-- 014000

MED-- 022000

MED-- 045000

MED-- 112000

MMFM

Number

Edition

Class number

Class number

Hilgenfeld, R., (Rolf)

Vasudevan, Subhash

Tofo Advanced Study Week on Emerging Viral Diseases(2nd :2016 :, Praia do Tofo, Mozambique)

Date of Transaction

20200823222934.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y