Front Cover; FUNDAMENTALS OF RADIATION ONCOLOGY; FUNDAMENTALS OF RADIATION ONCOLOGY; Copyright; Dedication; Contents; Foreword-James A. Bonner; Foreword-Thomas A. Buchholz; Preface; Contributors; Reviewers; I -- BASIC SCIENCE OF RADIATION ONCOLOGY; 1 -- Radiation Physics, Dosimetry, and Treatment Planning; FUNDAMENTAL PHYSICAL QUANTITIES; Mass; Energy; Charge; Force; ATOMIC STRUCTURE; Atomic Models; Electron Binding Energy; Atomic Shell Filling Rules; Characteristic Radiation; Auger Electrons; Nuclear Binding Energy; NUCLEAR STRUCTURE; RADIOACTIVE DECAY; MODES OF RADIOACTIVE DECAY; Alpha Decay
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3 -- Radiation BiologyRADIOBIOLOGICAL QUANTITIES; Directly and Indirectly Ionizing Radiation; Deposition of Ionizations Along Tracks; Direct and Indirect Effects of Radiation; Linear Energy Transfer; Relative Biological Effectiveness; Therapeutic Ratio; RADIATION EFFECTS ON CHROMOSOMES; Chromosome-Type Aberrations; Chromatid-Type Aberrations; Telomeres and Telomerase; Repair of Radiation Damage; CELL SURVIVAL CURVES; Target Theory; The Linear-Quadratic (L-Q) Model; The Four "R's" of Radiobiology; FRACTIONATION PROTOCOLS USED IN CLINICAL RADIOTHERAPY; DOSE RATE EFFECT AND REPAIR OF DAMAGE
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Beta DecayGamma Emission; Isomeric Transitions; Internal Conversion; Mathematics of Radioactive Decay; Activity; Equilibrium; ELECTROMAGNETIC RADIATION AND PROPERTIES OF INTERACTION; Photon Interaction Process, Kerma, Absorbed Dose; Modes of Photon Interaction; Mathematics of Photon Attenuation; PARTICULATE RADIATION PROPERTIES AND INTERACTIONS; Interactions of Electrons; Interactions of Neutrons; Interactions of Heavy Charged Particles; THE PHYSICS OF DOSIMETRY; Inverse Square Law; Backscatter Factor; Peak Scatter Factor; Depth of Maximum Dose (dmax); Percentage Depth Dose; Tissue-Air Ratio
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Image-Guided Radiation TherapyBRACHYTHERAPY; Interstitial Brachytherapy; Intracavitary Brachytherapy; OTHER RADIATION THERAPY MODALITIES; References; 2 -- Radiation Protection and Safety; MEASUREMENT OF RADIATION QUANTITIES; Radiation Exposure; Absorbed Dose; Effective Dose Equivalent; Effective Dose; RADIATION PROTECTION PRINCIPLES; ORGANIZATIONS; REGULATIONS; OCCUPATIONAL AND GENERAL PUBLIC DOSE LIMITS; ALARA AND RADIATION-INDUCED BIOLOGICAL EFFECTS; RADIATION TREATMENT ROOM DESIGN; SIGNAGE AND LABELING REQUIREMENTS; EQUIPMENT AND AREA MONITORING; PERSONNEL MONITORING; References
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Scatter-Air RatioTissue-Phantom Ratio, Tissue-Maximum Ratio; LINAC CALIBRATION; Types of Calibration; Field Size Correction Factors; Collimator Scatter Factor and Phantom Scatter Factor; Beam Modifier Factors; Patient Attenuation Factors; Calculation of Monitor Units and Treatment Time; Electron Beam Dosimetry; THE PHYSICS OF RADIATION TREATMENT PLANNING AND DELIVERY; External Beam Radiation; Internal Radiation; RADIATION TREATMENT PLANNING; EXTERNAL BEAM RADIATION THERAPY; 3-D Conformal Radiation Therapy; Intensity-Modulated Radiation Therapy; Volumetric Modulated Arc Therapy
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SUMMARY OR ABSTRACT
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Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Third Edition continues to provide current, concise, and a readily available source of clinical information for busy practicing radiation oncologists. The book consists of 26 chapters, divided into four parts: Part I describes the basic science of radiation oncology, with discussions of radiation physics, radiation protection, and radiation biology, as well as molecular biology. Part II describes techniques and modalities of radiation oncology including brachytherapy, intensity-modulated radiation therapy (IMRT), stereotactic radiotherapy (SRS), stereotactic body radiation therapy (SBRT), and proton therapy. Significant recent advances made in the areas of immunotherapy and combined modality therapy; as such, these chapters have also been added to this new edition. Part III describes the clinical science of radiation oncology including risk factors, symptoms/signs, and investigations needed for the cancer diagnosis and up-to-date treatment recommendations in accordance with the new AJCC staging system. In addition, radiation treatment techniques, with an emphasis on IMRT, have been expanded to all the chapters. Also included in this version of the book is a chapter on benign diseases. Updated annotated bibliographies of latest landmark studies providing evidence-based rationale for the recommended treatments are presented at the end of each chapter. Part IV describes palliative radiation treatments to improve the quality of life for cancer patients and the management of side effects from radiation treatment. This book is a must-have for all radiation oncology residents, radiation oncologists and all professionals engaged in the care of cancer patients.