a new introduction to molecular structure and function /
First Statement of Responsibility
Robert R. Crichton.
EDITION STATEMENT
Edition Statement
Third edition.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
London, United Kingdom :
Name of Publisher, Distributor, etc.
Academic Press, an imprint of Elsevier,
Date of Publication, Distribution, etc.
[2019].
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource.
GENERAL NOTES
Text of Note
Includes index.
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
An overview of the role of metals in biology -- Basic coordination chemistry for biologists -- Structural and molecular biology for chemists -- Biological ligands for metal ions -- An overview of intermediary metabolism and bioenergetics -- Methods to study metals in biological systems -- Metal assimilation pathways -- Intracellular metabolism and homeostasis of metal ions -- Sodium and potassium: channels and pumps -- Magnesium-Phosphate metabolism and photoreceptors -- Calcium -- cellular signalling -- Zinc -- Lewis acid and gene regulator -- Iron: essential for almost all life -- Copper -- coping with dioxygen -- Nickel and cobalt: evolutionary relics -- Manganese -- oxygen generation and detoxification -- Molybdenum, tungsten, vanadium and chromium -- Nonmetals in biology -- Biomineralization -- Metals in brain -- Metals and neurodegeneration -- Metals in medicine as drugs -- Metals in the environment.
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SUMMARY OR ABSTRACT
Text of Note
"Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions; intermediary metabolism and bioenergetics; and methods to study metals in biological systems. This valuable resource also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses non-metals in biology; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment, and much more."