عنوان

Targeting trafficking in drug development /

(Number (ISBN

3319741640

(Number (ISBN

9783319741642

Erroneous ISBN

3319741632

Erroneous ISBN

9783319741635

Title Proper

Targeting trafficking in drug development /

General Material Designation

[Book]

First Statement of Responsibility

Alfredo Ulloa-Aguirre, Ya-Xiong Tao, editors.

Place of Publication, Distribution, etc.

Cham, Switzerland :

Name of Publisher, Distributor, etc.

Springer,

Date of Publication, Distribution, etc.

2018.

Specific Material Designation and Extent of Item

1 online resource (viii, 425 pages) :

Other Physical Details

illustrations

Series Title

Handbook of experimental pharmacology,

Volume Designation

volume 245

ISSN of Series

0171-2004 ;

Text of Note

Includes bibliographical references.

Text of Note

1. Intracellular trafficking of gonadotropin receptors in health and disease -- 2. Investigating internalization and intracellular trafficking of GPCRs -- 3. Pharmacological chaperones as potential therapeutic strategies for misfolded mutant vasopressin receptors -- 4. Targeting of disordered proteins by small molecules in neurodegenerative diseases -- 5. Pharmacoperones for misfolded gonadotropin receptors -- 6. Pharmacological chaperones: Beyond conformational disorders -- 7. Natural (and unnatural) small molecules as pharmacological chaperones and inhibitors in cancer -- 8. Heritable skeletal disorders arising from defects in processing and transport of Type I procollagen from the ER: perspectives on possible therapeutic approaches -- 9. Conserved oligomeric Golgi and neuronal vesicular trafficking -- 10. SLC6 transporter folding diseases and pharmacochaperoning -- 11. The molecular physiopathogenesis of islet amyloidosis -- 12. Folding defects leading to primary hyperoxaluria -- 13. Potential pharmacological chaperones for cystathionine beta-synthase-deficient homocystinuria.

0

Text of Note

Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.

Source for Acquisition/Subscription Address

Springer Nature

Stock Number

com.springer.onix.9783319741642

Title

Targeting trafficking in drug development.

International Standard Book Number

9783319741635

Drug development.

Drug targeting.

Molecular pharmacology.

Drug Delivery Systems.

Drug Discovery.

Biomedicine.

Cell Biology.

Pharmacology/Toxicology.

Cellular biology (cytology)

Drug development.

Drug targeting.

MEDICAL-- Pharmacology.

Molecular pharmacology.

Pharmacology.

MED-- 071000

MMG

Number

Edition

Class number

Tao, Ya-Xiong

Ulloa-Aguirre, Alfredo

Date of Transaction

20200823104726.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y