عنوان
پدید آورنده
موضوع
رده
RC271.C5
RC271
.
C5
کتابخانه
محل استقرار
INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
3319679325
(Number (ISBN
9783319679327
Erroneous ISBN
3319679309
Erroneous ISBN
9783319679303
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Resistance to anti-cancer therapeutics targeting receptor tyrosine kinases and downstream pathways /
General Material Designation
[Book]
First Statement of Responsibility
Yosef Yarden, Moshe Elkabets, editors.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Cham, Switzerland :
Name of Publisher, Distributor, etc.
Springer,
Date of Publication, Distribution, etc.
2018.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource
SERIES
Series Title
Resistance to targeted anti-cancer therapeutics ;
Volume Designation
volume 15
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Resistance of colorectal tumors to anti-EGFR antibodies -- Resistance of lung cancer to kinase inhibitors specific to EGFR or ALK -- Mechanisms of action and resistance of trastuzumab in breast cancer -- Mechanisms of resistance to molecular therapies targeting the HGF/MET axis -- RAF, MEK and ERK inhibitors as anti-cancer drugs: intrinsic and acquired resistance as a major therapeutic challenge -- Mechanisms of resistance to PI3K and AKT inhibitors -- Sensitivity and resistance to BH3 mimetics in cancer therapy -- Resistance mechanisms to cyclin-dependent kinase inhibitors -- Resistance to inhibitors of angiogenesis.
0
SUMMARY OR ABSTRACT
Text of Note
This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression. Each chapter will cover a specific group of targets and the cognate drugs, along with molecular modes of innate and evolving resistance.
ACQUISITION INFORMATION NOTE
Source for Acquisition/Subscription Address
Springer Nature
Stock Number
com.springer.onix.9783319679327
OTHER EDITION IN ANOTHER MEDIUM
Title
Resistance to anti-cancer therapeutics targeting receptor tyrosine kinases and downstream pathways.
International Standard Book Number
3319679309
TOPICAL NAME USED AS SUBJECT
Antineoplastic agents.
Cancer-- Chemotherapy.
Drug resistance in cancer cells.
Antineoplastic agents.
Cancer-- Chemotherapy.
Drug resistance in cancer cells.
HEALTH & FITNESS-- Diseases-- General.
MEDICAL-- Clinical Medicine.
MEDICAL-- Diseases.
MEDICAL-- Evidence-Based Medicine.
MEDICAL-- Internal Medicine.
Oncology.
(SUBJECT CATEGORY (Provisional
HEA-- 039000
MED-- 014000
MED-- 022000
MED-- 045000
MED-- 112000
MJCL
DEWEY DECIMAL CLASSIFICATION
Number
616
.
99/4061
Edition
23
LIBRARY OF CONGRESS CLASSIFICATION
Class number
RC271
.
C5
PERSONAL NAME - ALTERNATIVE RESPONSIBILITY
Elkabets, Moshe
Yarden, Y., (Yosef)
ORIGINATING SOURCE
Date of Transaction
20200823102458.0
Cataloguing Rules (Descriptive Conventions))
pn
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب [Book]
Y
