عنوان

Animal models of acute neurological injury /

(Number (ISBN

3030160823

(Number (ISBN

9783030160821

Erroneous ISBN

9783030160807

Title Proper

Animal models of acute neurological injury /

General Material Designation

[Book]

First Statement of Responsibility

Jun Chen, Zao C. Xu, Xiao Ming Xu, John H. Zhang, editors.

Edition Statement

Second edition.

Place of Publication, Distribution, etc.

Cham, Switzerland :

Name of Publisher, Distributor, etc.

Springer,

Date of Publication, Distribution, etc.

[2019]

Specific Material Designation and Extent of Item

1 online resource

Series Title

Springer series in translational stroke research

Text of Note

Includes index.

Text of Note

Intro; Preface; Contents; Part I: Animal Care and Surgery; Animal Protocol; Regulatory Oversight; Designing the Animal Protocol; Writing the Animal Protocol; References; Anesthesia and Analgesia for Research Animals; Introduction; Pre-anesthetic Considerations and Monitoring; Injectable Anesthetics; Bartiturates; Ketamine; Propofol; Sedative/Tranquilizers; Local Anesthetics; Gaseous Agents; Isoflurane; Sevoflurane; Other Inhalants; Hypothermia; Analgesia; Opioids; Non-steroidal Anti-inflammatory Drugs (NSAIDs); Other Analgesics

Text of Note

Airway Management in the Rodent ModelIntubation; Materials; Procedures; Transcardiac Perfusion and Fixation; Equipment and Materials; Step by Step Procedures; Methods of Brain Removal; Materials; Procedures; Brain Removal; Separation of the Brain into Anatomical Sections; Materials; Procedure; Preparation of Brain Slices for Triphenyltetrazolium Chloride Staining; Materials; Procedure; References; Brain Monitoring; Introduction; Model Selection; Materials; Intravenous Femoral Catheter; Procedure; Burr Hole and Brain Monitoring; Postoperative Care; Conclusion; References

Text of Note

Placement of Occluding Device Around Carotid ArteryElectrocauterization of Vertebral Artery; Occlusion of Bilateral Common Carotid Arteries; One-Day 4-VO Model (with ID Recording); Surgical Preparation; ID Recording; Outcome Evaluation; Ischemic Cell Death in the Hippocampus; Ischemic Cell Death in the Striatum; Advantages, Complications and Limitations; Advantages; Complications; Limitations; Technical Difficulties; Mortality; Variation; References; Rat Model of Global Cerebral Ischemia: The Two-Vessel Occlusion (2VO) Model of Forebrain Ischemia; Introduction

Text of Note

Special Considerations-Anesthesia and Analgesia for Animal Models of Neurologic DiseasesCerebral Ischemia and Hemorrhage Models; Physiologic Effects of Anesthesia and the Impact on Cerebral Ischemia and Hemorrhage Models; Anesthetic Considerations; Analgesic Considerations; Traumatic Brain Injury Models; Anesthetic Considerations; Analgesic Considerations; Spinal Cord Injury Models; Physiologic Effects of Anesthesia and the Impact on SCI Models; Anesthetic and Analgesic Agents Impact Spinal Injury Models; References; Rodent Surgical Procedures and Tissue Collection; Introduction

Text of Note

Veterinary Care Methods for Rats and Mice in Experimental Spinal Cord Injury Studies: An UpdateModel Selection; Materials and Methods; Before Surgery and SCI; Surgery and SCI; Sterilization; Preparation; Surgery and SCI; Acutely and the First Week After Surgery and SCI; Housing; Veterinary Care; Chronically After Surgery and SCI; References; Part II: Cerebral Ischemic Animal Models; Four-Vessel Occlusion Model in Rats; Model Selection; Materials; Animal; Anesthesia; Equipment; Anesthesia; Surgery; Recording of Ischemic Depolarization; Procedures; Original 4-VO Model

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Text of Note

Despite numerous recent studies and exciting discoveries in the field, only limited treatments are available today for the victims of acute brain and spinal cord injuries. Animal Models of Acute Neurological Injuries, Second Edition, provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that often inhibit advances in this specialized research field. In the 10 years since publication of the first edition of this book, some animal models have become obsolete, some have stood the test of time, and newer models have emerged to enhance our knowledge of acute neurological injuries. The second edition continues to offer the research community tested approaches for this area of investigation. As with the first edition, top experts have developed and contributed these animal models. The books focus remains hands-on, practical applications of the models, rather than a theoretical approach. Each chapter contains a proven procedure enhanced by clear figures, illustrations, or videos. This new edition presents its readily reproducible protocols with clarity and consistency to best aid neuroscientists and neurobiologists. As with the first edition, the second edition is comprehensive and cutting-edge. Animal Models of Acute Neurological Injuries, Second Edition, is an ideal guide for research professionals, at all stages of their careers, who wish to pursue this vital course of study with the proficiency and precision required by the field.

Source for Acquisition/Subscription Address

Springer Nature

Stock Number

com.springer.onix.9783030160821

Title

Animal Models of Acute Neurological Injury.

International Standard Book Number

9783030160807

Nervous system-- Diseases-- Animal models, Handbooks, manuals, etc.

Nervous system-- Pathophysiology-- Animal models, Handbooks, manuals, etc.

Nervous system-- Wounds and injuries, Handbooks, manuals, etc.

Nervous system-- Diseases-- Animal models.

Nervous system-- Wounds and injuries.

MED057000

PSAN

PSAN

Number

Edition

Class number

Book number

Chen, Jun

Xu, Xiao-Ming

Xu, Zao C.

Zhang, J. H., (John H.)

Date of Transaction

20200823084935.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y