Intro; Acknowledgments; Contents; Contributors; Part I; 1: The Changing Face of HIV; Historical Perspective; Epidemiology of HIV/AIDS; HIV-1 Life Cycle and Antiretroviral Therapy; Increased Risk for Cardiovascular Disease; Patients Living with HIV at Risk for Cardiovascular Disease: Etiologies; References; Part II; 2: Risk Prediction; Risk Stratification and Scores; Existing Risk Stratification Schemes for the General Population; National Cholesterol Education Program Adult Treatment Panel; 2013 American College of Cardiology and the American Heart Association Guidelines
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2014 National Lipid Association RecommendationsProposed Risk Stratification Schemes for HIV-Infected Patients; Data Collection on Adverse Effects of Anti-HIV Drugs; Veterans Aging Cohort Study; Use of Risk Stratification Schemes for the General Population in Patients Infected with HIV; Additional Measures of Risk; Measures of Subclinical Atherosclerosis; CD4 Count and Viral Load; Recommendations for Risk Stratification for Patients Infected with HIV; References; 3: Diagnosis and Management of Dyslipidemia; Introduction; HIV and Risk for Cardiovascular Disease
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5: Diabetes, Prediabetes, and Metabolic Syndrome Among People Living with HIVIntroduction; Screening for Diabetes; Epidemiology of Diabetes; Incidence of Diabetes and HIV; Prevalence of Diabetes and HIV; Classification of Diabetes and HIV; Pathogenesis; Host Factors; HIV Infection Factors; Coinfection with Hepatitis C Virus (HCV); Autoimmunity; Medications; Antiretroviral Medications; Protease Inhibitors; Nucleoside Reverse Transcriptase Inhibitors; Other Medications/Drugs; Other Factors; Management of Diabetes and Prediabetes; Lifestyle and HIV Treatment Changes; Prediabetes; Diabetes
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Lipid Changes with HIV Infection and ARTGuidelines for the Management of Dyslipidemia in Patients Infected with HIV; Risk Stratification and Scores; Lipid Targets for Patients Living with HIV; LDL-C; Residual Risk; Triglycerides; HDL Cholesterol; Step-by-Step Management of Dyslipidemia in Patients Infected with HIV; When to Use Measures of Residual Risk; History and Physical Examination; Laboratory Evaluation; Therapeutic Lifestyle Modification; Medications: Treatment of LDL Cholesterol; Statins; Efficacy; Drug-Drug Interactions Between ART, Pharmacoenhancers, and Statins
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Side Effects of Statin DrugsLiver Side Effects; Muscle; Neurologic; Diabetes and Insulin Resistance; Non-statin Drugs for the Treatment of Dyslipidemia; Intestinal Absorption Inhibitors; Niacin (Nicotinic Acid); Bile Acid Sequestrants; Treatment of Hypertriglyceridemia; Fibrates; Fish Oil; Niacin; Other Issues Related to Drug Therapy; Cost of Drugs and Coverage; Combination with Other Non-statin Drugs; Familial Hypercholesterolemia; Switching ART; Monitoring and Follow-Up; Conclusion; References; 4: Hypertension in HIV; Diagnosis; Initiation of Pharmacologic Therapy; References
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SUMMARY OR ABSTRACT
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This book provides the most current overview of the evaluation and management of cardiovascular disease in people living with HIV/AIDS. The text assesses the risk factors associated with cardiovascular disease in HIV/AIDS patients and explores the most cutting edge ways to diagnose and treat the specific diseases that are most common for people living with HIV. This text takes a well-rounded, multidisciplinary approach that considers infectious disease and HIV specialists who may have little familiarity with the diagnosis and management of manifest CVD or risk factors as well as those in remote areas where providers may have little or no infrastructure to support optimal care for their patients. The text also serves cardiovascular specialists who may not have the expertise in HIV care to meet the unique needs of these patients. Cardiovascular Care for the Patient Living with HIV is the ultimate resource for not only all infectious disease and HIV specialists, but also for cardiologists, neurologists, vascular surgeons, general practitioners, nurse practitioners, physician?s assistants, and all other medical professionals who care for people living with HIV.