Cardiorespiratory Fitness in Cardiometabolic Diseases :
General Material Designation
[Book]
Other Title Information
Prevention and Management in Clinical Practice /
First Statement of Responsibility
editors, Peter Kokkinos and Puneet Narayan.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Cham, Switzerland :
Name of Publisher, Distributor, etc.
Springer,
Date of Publication, Distribution, etc.
[2019]
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Intro; Preface; Contents; Contributors; 1: Physical Activity, Cardiorespiratory Fitness, and Health: A Historical Perspective; Introduction; Physical Activity and Health Connection; Physical Activity in the United States; Physical Activity, Exercise Capacity, and Health; A Call to Action; Final Note; References; 2: Exercise, Gene Regulation, and Cardiometabolic Disease; Introduction; Gene Regulation; Transcription Factor Binding; Epigenetic Control: Histone Modifications; Epigenetic Control: DNA Methylation; miRNA; Gene Regulation in CMD; Transcription Factors and Co-regulators
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Epigenetic Modifications of the MitochondriaExercise Effect on Mitochondria; Interventional Evidence and Mechanisms of Exercise-Induced Changes Coupled to the Mitochondria; Clinical and Public Health Relevance; Conclusion and Future Directions; References; 4: Effect of Exercise on Adult Stem Cells; Introduction; Adult Stem Cells Are Influenced by Exercise; Effect of Exercise on Endothelial Progenitor Cells (EPCs) and Mesenchymal Stromal Cells (MSCs); Effects on EPCs; Effects on MSC; Conclusion; References; 5: Exercise Metabolism in Health and Disease; Exercise Metabolism: An Overview
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Muscle Fiber TypesEnergy Substrates; ATP; Phosphocreatine (PCr); Glycogen; Lipids; Metabolic Pathways; Anaerobic Metabolism During Exercise; The ATP-PCr System; Glycolysis; Regulation of Anaerobic Pathways; Lactate Metabolism; Lactate Threshold: How Is It Affected by Fitness?; Can the Lactate Threshold Be Altered?; Aerobic Metabolism During Exercise; Carbohydrate Metabolism; Regulation of Hepatic Glucose Production; Regulation of Muscle Glucose Uptake; Cross Talk Between Skeletal Muscle and Liver Metabolism in Exercise; Fat Metabolism; Regulation of Muscle Fat Metabolism
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Proteins as an Energy Source During ExerciseFactors Determining Substrate Preference During Exercise; Sex-Related Differences in Substrate Preference During Exercise; Cardiac Metabolism During Exercise; Metabolism of Energy Substrate in Heart During Exercise; Glucose; Free Fatty Acids; Ketone Bodies; Amino Acids; Preferred Substrate for Energy Needs of the Heart During Exercise; Molecular Mechanisms of Exercise-Induced Metabolic Adaptations in Cardiac Muscle; Future Considerations of Cardiac Metabolism; Exercise-Induced Chronic Metabolic Adaptations; Hormonal Regulation of Exercise Metabolism
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Transgenerational EpigeneticsInflammation and CMD; miRNA and CMD; Treatments for CMD to Alter Gene Expression; Gene Regulation with Exercise; Inflammation and Exercise; miRNA; Variability in Training Response; Conclusions; References; 3: Exercise and the Mitochondria; Introduction; The Magical Mitochondria; Heart Muscle Mitochondria; Mitochondrial Replication, Transcription, and Biogenesis; Replication; Transcription; Biogenesis; Mitochondrial Medicine; Mitochondrial Disorders; Mitochondrial Dysfunction; Aging and Longevity in Connection to Mitochondria
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SUMMARY OR ABSTRACT
Text of Note
This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as the elderly and people of various racial backgrounds. The book also highlights risks associated with exercise and presents a prescription for appropriate and efficacious exercise to minimize risk and maximize health benefits for the heart. Cardiorespiratory Fitness in Prevention and Management of Cardiometabolic Disease is an essential resource for physicians, exercise physiologists, medical students, residents, fellows, nurses, and researchers in cardiology, cardiorespiratory fitness, exercise science, health promotion and disease prevention, public health, and epidemiology.