عنوان

Prefoldins :

(Number (ISBN

3030007375

(Number (ISBN

9783030007379

Erroneous ISBN

3030007367

Erroneous ISBN

9783030007362

Title Proper

Prefoldins :

General Material Designation

[Book]

Other Title Information

the new chaperones /

First Statement of Responsibility

Nabil Djouder, editor.

Place of Publication, Distribution, etc.

Cham :

Name of Publisher, Distributor, etc.

Springer,

Date of Publication, Distribution, etc.

[2018]

Specific Material Designation and Extent of Item

1 online resource

Series Title

Advances in experimental medicine and biology

Text of Note

Includes index.

Text of Note

Includes bibliographical references and index.

Text of Note

Preface -- Structure of the molecular chaperone prefoldin -- Structure and function of archaeal prefoldin -- Role and functions of prefoldins -- Nuclear functions of prefoldins -- The yeast prefoldin Bud27 -- URI-like prefoldin complex -- HSP90 and its R2TP/Prefoldin-like cochaperone -- Role and functions of URI: mouse models for URI -- Nuclear function of URI-like prefoldin complex -- URI and androgen regulation. Index.

0

Text of Note

This book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure. Even though, there is still a lot to investigate in order to understand the roles and functions of prefoldins, some preliminary work suggests their contribution in assembly and activation of a variety of macromolecular complexes. Hence, the reader is introduced to recent structural findings via cryo-electron microscopy and to the importance of this particular group of proteins in health and disease. This book also discusses the particular structure of the URI prefoldin-like complex. In addition, recent developments in the generation of URI mouse models speculate on the functions and emerging roles of the URI prefoldin-like complex in various cellular processes. This novel protein complex represents a unique cellular machinery, which molecular basis of its activity still remains to be determined. This work is thus a guide to help researchers in the field to have a more comprehensive and critical view of the prefoldin world.

Source for Acquisition/Subscription Address

Springer Nature

Stock Number

com.springer.onix.9783030007379

Title

Prefoldins.

International Standard Book Number

9783030007362

Molecular chaperones.

Intracellular Signaling Peptides and Proteins.

Molecular Chaperones.

Protein Conformation.

Molecular chaperones.

MED107000

MFN

MFN

Number

Edition

Class number

Book number

Class number

Djouder, Nabil.

Date of Transaction

20200823072142.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y