عنوان

Gravitational biology.

(Number (ISBN

3030005968

(Number (ISBN

9783030005962

Erroneous ISBN

9783030005955

Title Proper

Gravitational biology.

General Material Designation

[Book]

First Statement of Responsibility

Wolfgang Hanke, Florian P.M. Kohn, Maren Neef, Rüdiger Hampp.

Volume Designation

II,dollar5Interaction of gravity with cellular components and cell metabolism /

Place of Publication, Distribution, etc.

Cham :

Name of Publisher, Distributor, etc.

Springer,

Date of Publication, Distribution, etc.

2018.

Specific Material Designation and Extent of Item

1 online resource (xiv, 94 pages)

Series Title

SpringerBriefs in space life sciences

Text of Note

Intro; Preface to the Series; Preface; Acknowledgements; Contents; Chapter 1: Interaction of Gravity with Cellular Compounds; 1.1 Introduction; 1.2 Structure and Function of the Neuronal System; 1.3 Biological Membranes; 1.4 Neuronal Cells; 1.5 Thermodynamics of Neuronal Systems; 1.6 Interaction of Gravity with Single Molecules; 1.7 Interaction of Gravity with Membranes; 1.8 Interaction of Gravity with Neuronal Cells; 1.9 Membrane Potential; 1.10 Action Potentials; 1.11 Cytosolic Calcium Concentration; 1.12 Discussion and Consequences; 1.13 Modeling the Gravity Dependence of Neuronal Tissue

Text of Note

1.14 Space Pharmacology1.15 Outlook and Future Perspectives; References; Chapter 2: Interaction of Gravity with Cell Metabolism; 2.1 Introduction; 2.2 Methods; 2.2.1 Opportunities for Exposure; 2.2.1.1 Centrifugation; 2.2.1.2 Clinorotation; 2.2.1.3 Random Positioning; 2.2.1.4 Magnetic Levitation; 2.2.1.5 Space Shuttle and Satellite; 2.2.1.6 Sounding Rockets; 2.2.1.7 Parabolic Flights: Hyper-g, Partial g, and Microgravity; 2.2.2 Plant Material; 2.2.3 Determination of Key Metabolites; 2.2.4 Metabolic Labeling with (14C)-Glucose; 2.2.5 Real-Time Analysis of Ca2+ and Hydrogen Peroxide

Text of Note

2.2.6 Gene and Protein Expression2.3 Results; 2.3.1 Metabolism; 2.3.2 Secondary Messengers: Calcium and Hydrogen Peroxide; 2.3.3 Gene Expression; 2.3.3.1 Expression of Genes Coding for Primary Metabolism; 2.3.3.2 Expression of Genes Coding for Transcription Factors; Time-Course Experiments: Hyper-g and Simulation of Microgravity; Effects of Microgravity: MAXUS 7; Functions of TFs; 2.3.3.3 Conclusion for Transcription Factor Studies; 2.3.4 Array Studies; 2.3.4.1 Macroarrays (``Home Made)́́; 2.3.4.2 Early Microarrays (Incyte Genomics); 2.3.4.3 Affymetrix Microarrays; 2.3.5 Platforms

Text of Note

2.3.6 Protein Expression and Modulation2.3.6.1 Hypergravity; 2.3.6.2 2-D Clinorotation; 2.3.6.3 Random Positioning; Phosphoproteom; Two-dimensional SDS Polyacrylamide Gel Electrophoresis; 2.3.6.4 Protein Labeling; 2.3.6.5 Evaluation of Simulation of Microgravity; 2.3.6.6 How We Think that a Gravity-Related Line of Plant Responses Works: Secondary Messengers, Genes, and Proteins; ROS Scavenging and Detoxifying Enzymes; Signal Transduction; Metabolism; Protein Translation and Proteolysis; Cell Wall Biosynthesis; Ion homeostasis; 2.4 Conclusions; References

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Text of Note

This volume of the series Space Life Sciences provides insights into the latest findings of gravity research and the effect of gravity on biological systems, specifically on a cellular and molecular level. It starts by explaining the underlying physics of gravity and presenting some novel ideas on the basic principles of gravity perception. It then goes on to discuss how, in response to gravity perception, secondary messengers such as calcium and hydrogen peroxide, might control responses further downstream, like gene and protein expression and modulation. Further, it describes the consequences for animal and plant cells as well as for metabolism. Written by experts in the field, this book is a valuable resource for students and researchers in biochemistry, medicine and biomedicine, wanting to gain a solid understanding of membrane biology, secondary messenger function and gene and protein expression, specifically in the context of gravity.

Source for Acquisition/Subscription Address

Springer Nature

Stock Number

com.springer.onix.9783030005962

International Standard Book Number

9783030005955

Biotechnological microorganisms.

Gravity-- Physiological effect.

Microorganisms.

Aerospace Technology and Astronautics.

Biological and Medical Physics, Biophysics.

Human Physiology.

Membrane Biology.

Neurosciences.

Plant Sciences.

Biotechnological microorganisms.

Gravity-- Physiological effect.

Microorganisms.

MED075000

MFG

MFG

Number

Edition

Class number

Book number

Hanke, Wolfgang

Hampp, Rüdiger

Kohn, Florian P. M.

Neef, Maren

Date of Transaction

20200823071954.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y