Cancer biotherapy: general principles -- Pathogenesis of cancer metastasis: relevance to biotherapy -- Developmental therapeutics and the design of clinical trials -- Recombinant proteins and genomics in cancer therapy -- Current concepts in immunology -- Therapeutic approaches to cancer-associated immune suppression -- Cancer vaccines -- Cytokines -- Interferons: therapy for cancer -- Monoclonal antibody therapy -- Immunotoxins -- Drug immunoconjugates -- Radiolabeled antibodies for the management of metastatic cancer -- Stem-cell/bone-marrow transplantation as biotherapy -- Recent advances in the cellular immunotherapy of human cancer -- Growth and differentiation factors as cancer therapeutics -- Granulocyte colony-stimulating factor: biology and clinical potential -- Biochemical purification and molecular and biologic characterization -- Cancer gene therapy -- Cancer biotherapy: 1996 disease-related activity -- Speculations for 2003 and beyond.