Cover; Title Page; Copyright Page; PREFACE; ACKNOWLEDGMENTS; THE EDITOR; CONTRIBUTORS; Table of Contents; Chapter 1: pH-Selective Microelectrodes: Construction and Use in Investigation of Transmembrane Sodium/Hydrogen Exchange; Chapter 2: Measurement of pH and Na+ by Nuclear Magnetic Resonance; Chapter 3: Methods for the Study of Na+ /H+ Exchange: Ion-Selective Electrodes; BASIC PROPERTIES AND DISTRIBUTION OF THE Na+ /H+ EXCHANGER; Chapter 4: Kinetics of Na+ /H+ Exchange; Chapter 5: Na+ /H+ Exchange in Excitable Cells; Chapter 6: Properties of Na+ /H+ Exchange in Excitable Cells
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Chapter 13: Symports and Antiports in Epithelial Cell Volume RegulationChapter 14: Coupling between Na+/H+ and Cl-/HC03 Exchange in pH and Volume Regulation; Chapter 15: The Role of Na+ /H+ Exchange and Intracellular pH Changes in Fertilization; REGULATION OF Na+/H+ EXCHANGE: RAPID EFFECTORS; Chapter 16: Effects of Growth Factors on Na+ /H+ Exchange; Chapter 17: Phorbol Esters and the Regulation of Na+ /H+ Exchange; Chapter 18: Regulation of Na+ /H+ Exchange: Role of Ca2+; Chapter 19: Effects of Catecholamines and Cyclic Nucleotides on Na+ /H+ Exchange
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Chapter 20: Effects of Neutrophil and Platelet ActivatorsChapter 21: Action of Insulin on Na+ /H+ Exchange; REGULATION OF NA+ /H+ EXHANGE: SLOW (ADAPTIVE) EFFECTORS; Chapter 22: Regulation of Na+ /H/up Exchange Activity by Adaptive Mechansims; Chapter 23: Chronic Adaptation of Na+ /H + Exchange in Renal Disease; GENETIC STUDIES OF Na+ /H+ EXCHANGE; Chapter 24: Molecular Genetics of the Mammalian Na+ /H+ Antiporter; Index
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Chapter 7: Na+ /H+ Exchange in Bacteria and OrganellesINHIBITORS AND LIGANDS OF THE NA+ /H+ EXCHANGER; Chapter 8: Amiloride: Chemistry, Kinetics, and Structure-Activity Relationships; PHYSIOLOGICAL ROLE OF THE Na+ /H+ EXCHANGER; Chapter 9: Basic Principles of pH Regulation; Chapter 10: The Role of the Na+ /H+ Antiport in Cardiac Cells, Skeletal Muscle Cells, Neuronal Cells and Glial Cells; Chapter 11: Physiological Role of Na+/H+ Exchange in Epithelial Cells; Chapter 12: Na+/H+ Exchange and Volume Regulation in Nonepithelial Cells
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SUMMARY OR ABSTRACT
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Prepared by leading scientists in the field, these volumes compile for the first time, concise, up-to-date reviews of several aspects of the basic properties, distribution, function and regulation of the Na+/H+ antiport. In addition, current methods and the use of inhibitors and ligands for the study of the exchanger are described. These volumes are indispendable to researchers and students in the areas of ion transport, membrane biology and cellular physiology.