عنوان

MicroRNA :

(Number (ISBN

1351679872

(Number (ISBN

9781351679879

Erroneous ISBN

1138054836

Erroneous ISBN

1621001520

Erroneous ISBN

9781138054837

Erroneous ISBN

9781621001522

Title Proper

MicroRNA :

General Material Designation

[Book]

Other Title Information

perspectives in health and diseases /

First Statement of Responsibility

edited by Jaishree Paul, Rohini Muthuswami.

Place of Publication, Distribution, etc.

Boca Raton, FL :

Name of Publisher, Distributor, etc.

CRC Press,

Date of Publication, Distribution, etc.

2018.

Specific Material Designation and Extent of Item

1 online resource (xiv, 202 pages)

Text of Note

Includes bibliographical references and index.

Text of Note

Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Foreword -- Preface -- Editors -- Contributors -- Chapter 1: Controlling the Biogenesis of the Smallest Regulators -- 1.1 Transcription of miRNA Genes -- 1.2 Factors Regulating the Transcription of miRNA Genes -- 1.3 Processing of the Primary miRNA Transcript -- 1.4 Control of miRNA Biogenesis -- 1.4.1 At the Nuclear Processing Step -- 1.4.2 Nuclear Export of Pre-miRNA -- 1.5 Processing of the Precursor miRNA Transcript -- 1.5.1 Control of miRNA Biogenesis at the Cytoplasmic Processing Step -- 1.5.2 RNA Induced Silencing Complex -- 1.5.3 Repression/Decay of Target mRNA -- 1.6 Conclusion -- REFERENCES -- Chapter 2: Computational Analysis of miRNAs, Their Target Sequences and Their Role in Gene Regulatory Networks -- 2.1 MiRBase -- 2.2 Computational Identification of miRNA Genes -- 2.2.1 Sequence and Structure Conservation -- 2.2.2 Machine Learning Approach -- 2.2.3 Experimental Data-Driven Approach -- 2.2.4 In-House Computational Pipelines -- 2.3 Computations in Target Prediction -- 2.4 miRNA and Gene Regulatory Network -- 2.5 Conclusion -- References -- Chapter 3: miRNAs: Small RNAs with Big Regulatory Functions in Parasitic Diseases -- 3.1 miRNAs: Small RNAs with Big Regulatory Functions -- 3.2 Intracellular Protozoan Pathogens -- 3.2.1 Alteration of Host miRNAs by Apicomplexans -- 3.2.1.1 Modulation of Host microRNome by Kinetoplastids -- 3.3 Extracellular Protozoan Parasites -- 3.4 MICRORNAs in Parasitic Helminthiases -- 3.5 Concluding Remarks -- References -- Chapter 4: Role of miRNA in Multiple Sclerosis -- 4.1 Role of Oligodendrocyte and miRNA -- 4.2 Role of Immune Cell in MS Pathogenesis -- 4.2.1 Role of Th Cell miRNAs in MS -- 4.2.2 Role of Treg Cell miRNAs in MS -- 4.3 Role of Viral miRNA in MS -- 4.4 Experimental Autoimmune Encephalomyelitis (EAE) Model.

0

Text of Note

This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology.

Source for Acquisition/Subscription Address

Ingram Content Group

Stock Number

9781351679879

Title

MicroRNA.

Title

MicroRNA.

International Standard Book Number

1138054836

MicroRNA-- Health aspects.

Small interfering RNA.

MicroRNAs.

RNA, Small Interfering.

SCIENCE-- Life Sciences-- Biochemistry.

Small interfering RNA.

SCI-- 007000

Number

Edition

Class number

Book number

Class number

Muthuswami, Rohini

Paul, Jaishree

Date of Transaction

20200822160614.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y