عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
NATIONAL BIBLIOGRAPHY NUMBER
Number
TL49387
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Identification of Genetic Factors in the Etiology of Autism Spectrum Disorder in Arab Families
General Material Designation
[Thesis]
First Statement of Responsibility
Yasser Ammar AlSarraj
Subsequent Statement of Responsibility
El-Agnaf, Omar M.; El-Shanti, Hatem
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
Hamad Bin Khalifa University (Qatar)
Date of Publication, Distribution, etc.
2017
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
61
GENERAL NOTES
Text of Note
Committee members: Abdelalim, Essam M.; Akaaboune, Mohammed; Al Thani, Dena A.
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Place of publication: United States, Ann Arbor; ISBN=978-1-369-80566-6
DISSERTATION (THESIS) NOTE
Dissertation or thesis details and type of degree
M.S.
Discipline of degree
Science and Engineering
Body granting the degree
Hamad Bin Khalifa University (Qatar)
Text preceding or following the note
2017
SUMMARY OR ABSTRACT
Text of Note
Autism spectrum disorder (ASD) is a social interaction and communication impairment, associated with repetitive behaviors and interests. ASD has a high worldwide prevalence of about 1-1.5%. ASD is usually accompanied with heterogeneous phenotypic comorbidities, such as epilepsy and intellectual disability (ID). Twin studies suggest a high genetic contribution to ASD etiology, and several well-known rare genetic disorders are associated with ASD with high susceptibility contribution risk at about 0.5-1% of ASD cases. Moreover, several environmental factors and chromosomal abnormalities may increase the risk; the estimated known ASD-related genetic etiology is identifiable in about 25% of all ASD cases. Nevertheless, in about 75% of ASD cases the genetic etiologies remain elusive. The occurrence of ASD in the Middle East is not clear and there is a need to fill the gap in its clinical and genetic characterization in the Arab populations.
TOPICAL NAME USED AS SUBJECT
Genetics; Bioinformatics
UNCONTROLLED SUBJECT TERMS
Subject Term
Biological sciences;ASD;Autism;Whole Exome Sequencing
PERSONAL NAME - PRIMARY RESPONSIBILITY
Elbelazi, Samah A.
PERSONAL NAME - SECONDARY RESPONSIBILITY
El-Agnaf, Omar M.; El-Shanti, Hatem
CORPORATE BODY NAME - SECONDARY RESPONSIBILITY
Subdivision
Science and Engineering
Hamad Bin Khalifa University (Qatar)
LOCATION AND CALL NUMBER
Call Number
1909332738; 10285241
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب p
[Thesis]
276903
a
Y
