عنوان

25 years of p53 research.

(Number (ISBN

1402065647

(Number (ISBN

9781402065644

Number

b600824

Title Proper

25 years of p53 research.

General Material Designation

[Book]

Place of Publication, Distribution, etc.

Berlin

Name of Publisher, Distributor, etc.

Springer

Date of Publication, Distribution, etc.

2007

Specific Material Designation and Extent of Item

pages

Text of Note

Chapter 1 THE FIRST TWENTY-FIVE YEARS OF P53 RESEARCH --; Chapter 2 REGULATION OF P53 DNA BINDING --; Chapter 3 20 YEARS OF DNA DAMAGE SIGNALING TO P53 --; Chapter 4 GATEKEEPERS OF THE GUARDIAN: P53 REGULATION BY POST- TRANSLATIONAL MODIFICATION, MDM2 AND MDMX --; Chapter 5 REGULATION OF THE P53 RESPONSE BY CELLULAR GROWTH AND SURVIVAL FACTORS --; Chapter 6 P53, CELL CYCLE ARREST AND APOPTOSIS --; Chapter 7 P53 HAS A DIRECT PRO-APOPTOTIC ACTION AT THE MITOCHONDRIA --; Chapter 8 MANIPULATING THE P53 GENE IN THE MOUSE: ORGANISMAL FUNCTIONS OF A PROTOTYPE TUMOR SUPPRESSOR --; Chapter 9 P53, P63, AND P73: INTERNECINE RELATIONS? --; Chapter 10 P73, P63 AND MUTANT P53: MEMBERS OF PROTEIN COMPLEXES FLOATING IN CANCER CELLS --; Chapter 11 P53: GATEKEEPER, CARETAKER OR BOTH? --; Chapter 12 ANALYSIS OF P53 GENE ALTERATIONS IN CANCER: A CRITICAL VIEW --; Chapter 13 PATTERNS OF TP53 MUTATIONS IN HUMAN CANCER: INTERPLAY BETWEEN MUTAGENESIS, DNA REPAIR AND SELECTION --; Chapter 14 PROGNOSTIC AND PREDICTIVE VALUE OF TP53 MUTATIONS IN HUMAN CANCER --; Chapter 15 P53 LINKS TUMOR DEVELOPMENT TO CANCER THERAPY --; Chapter 16 NOVEL P53-BASED THERAPIES: STRATEGIES AND FUTURE PROSPECTS --; Chapter 17 WILD- TYPE P53 CONFORMATION, STRUCTURAL CONSEQUENCES OF P53 MUTATIONS, AND MECHANISMS OF MUTANT P53 RESCUE --; Chapter 18 MUTANTP53 REACTIVATION AS A NOVEL STRATEGY FOR CANCER THERAPY --; Chapter 19 NOVEL APPROACHES TO P53-BASED THERAPY: ONYX- 015 --; Chapter 20 P53 AS SEEN BY AN OUTSIDER --; INDEX.

Molecular biology -- Research.

p53 antioncogene.

p53 protein.

Class number

Book number

Electronic name

[Book]

Y