NATO ASI series., Series C,, Mathematical and physical sciences ;, 492.
CONTENTS NOTE
Text of Note
Modification of cyclodextrins to control their guest-host chemistry and their application as chemosensors --; New fluorescent readouts for protein interactions, gene expression, and membrane potential --; Chemical sensors based on field effect transistors; selective recognition of cations and anions --; Aqueous sugar sensing by boronic-acid-based artificial receptors --; Solid state supramolecular optical sensors --; Fluorescent chemosensors which take profit from the metalligand interaction --; Recognition, transduction and immobilisation- A holistic approach to sensor development --; Signal transduction in chemosensors of modified cyclodextrins --; Hydrogen bonding chemosensors for metabolites and nucleotides --; New approaches to sensory materials: Molecular recognition in conjugated polymers. New transduction methodology --; Higher generation luminescent PET (photoinduced electron transfer) sensors --; Chemosensing of monocyclic and bicyclic aromatic hydrocarbons by supramolecular active sites --; Squaraine-based long wavelength fluorescent chemosensors for ions --; A fluorescent chemosensor with selectivity for Hg(II). Chelatoselectivity via ligand immobilization --; Cation-responsive fluorescent sensors --; Fluorescent, siderophore-based hydroxamate chelators for the detection of transition-metalions --; Author index.
SUMMARY OR ABSTRACT
Text of Note
The design and use of chemosensors for ion and molecule recognition - a branch of supramolecular chemistry - have developed at an extraordinary rate. This imaginative and creative area involves work at the interface of organic and inorganic chemistry, physical chemistry, biology, medicine and environmental science and is providing new sensors based on the specific signal delivered by the analyte-probe reaction. The emergence of efficient fluorescent receptors has allowed the detection, identification, and even titration of, for example, heavy metal or radionuclide pollutants. Further, with sensors displaying specific and strong complexation properties, such materials could be detected and removed at very low concentrations. Further, among other species of biological interest, sugars, oxygen and carbon dioxide can actually be probed with optodes and similar devices. This is clearly just the beginning of a very promising line of research. Audience: Organic chemists interested in creating new chemosensors, as well as the many potential end users of such sensors.
PARALLEL TITLE PROPER
Parallel Title
Proceedings of the NATO Advanced Research Workshop on Chemosensors of Ion and Molecule Recognition, Bonas, France, August 31-September 4, 1996