عنوان

Is Crohn's Disease a Mycobacterial Disease?

(Number (ISBN

9401118302

(Number (ISBN

9789401118309

Number

b594932

Title Proper

Is Crohn's Disease a Mycobacterial Disease?

General Material Designation

[Book]

First Statement of Responsibility

edited by Chris J.J. Mulder, Guido N.J. Tytgat.

Place of Publication, Distribution, etc.

Dordrecht

Name of Publisher, Distributor, etc.

Springer Netherlands

Date of Publication, Distribution, etc.

1992

Specific Material Designation and Extent of Item

(vii, 77 pages)

Series Title

Developments in gastroenterology, 14.

Text of Note

Historical overview and current approaches in determining a mycobacterial etiology of Crohn's disease --; Mycobacterial isolates from Crohn's disease in the Netherlands --; Attempts at culturing mycobacteria from issues of patients with Crohn's disease --; Immunohistological evidence for mycobacteria in Crohn's disease --; Mycobacterium paratuberculosis and Crohn's disease --; Rabbits and severe combined immunodeficient (SCID) mice as animal models for mycobacteria in Crohn's disease --; Immunotherapeutical approaches to Crohn's disease in view of a possible pathogenic role of mycobacterial antigens --; Is immunotherapy with mycobacterium vaccae appropriate to Crohn's disease? --; Mycobacterial etiology of Crohn's disease: how to prove causation.

Text of Note

The fact that the differential diagnosis of inflammatory bowel disease includes intestinal infections has been a source of much interest and clinical concern for many years. Since the recognition of ulcerative colitis and Crohn's disease as clinical entities, numerous attempts have been made to identify a specific organism resulting in the clinical and pathologic picture of inflammatory bowel disease. The isolation, in 1984, of M. paratuberculosis initiated the current interest in and controversy about a mycobacterial etiology in Crohn's disease. The hypothesis that 'Crohn's disease is Johne's disease' has led to a number of efforts, world-wide, to determine whether or not mycobacteria are associated with Crohn's disease. The most active research groups have contributed to this book, describing their attempts to unravel the hypothesis, providing the reader with an up-to-date review of knowledge available up to Fall, 1992. The book is based in part on presentations to the symposium on Crohn's disease held during European Digestive Disease Week, Amsterdam, 24 October 1992. The contributions have been especially updated for publication.

Gastroenterology.

Medicine.

Microbiology.

Class number

Book number

edited by Chris J.J. Mulder, Guido N.J. Tytgat.

Chris J J Mulder

Guido N J Tytgat

Electronic name

[Book]

Y