I Clinical Pharmacology --; 1 The biological basis of benzodiazepine actions --; 2 Clinical pharmacokinetics of the benzodiazepines --; 3 Pharmacokinetic considerations in the treatment of chronic anxiety --; II Therapeutic Application --; 4 An international overview --; 5 Principles of therapeutic applications of benzodiazepines --; 6 Benzodiazepines in emotional disorders --; 7 Anxiety --; 8 Clinical comparison of benzodiazepine hypnotics with short and long elimination half-lives --; 9 Seizure disorders --; 10 Alcohol and other drug withdrawals --; 11 Additional clinical uses of benzodiazepines --; 12 Vital uses of diazepam in third world countries --; III Non-medical Use, Misuse and Abuse --; 13 Abuse and dependency: an international perspective --; 14 Experimental abuse liability assessment of benzodiazepines --; 15 Abuse liability of benzodiazepines: A review of human studies evaluating subjective and/or reinforcing effects --; 16 Acute and chronic toxicity of benzodiazepines --; IV Dependence --; 17 Benzodiazepine dependency syndromes --; V Social-Cultural Issues --; 18 The benzodiazepines: public health, social and regulatory issues. An industry perspective --; 19 Benzodiazepines: international legislation and relation to the Convention on Psychotropic Substances 1971 --; Appendices --; 1 Cross-reference of investigational, generic and trade names --; 2 Books on benzodiazepines.