عنوان

Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance :

(Number (ISBN

8847020859

(Number (ISBN

9788847020856

Number

b591247

Title Proper

Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance :

General Material Designation

[Book]

Other Title Information

From Basic to Clinical Research

First Statement of Responsibility

edited by Eugenio E. Müller.

Place of Publication, Distribution, etc.

Milano

Name of Publisher, Distributor, etc.

Springer Milan

Date of Publication, Distribution, etc.

2003

Specific Material Designation and Extent of Item

(xii, 197 pages)

Text of Note

LHRH/Somatostatin --; Chapter1 Twenty-five Years of Endocrine Oncology with Analogs of Hypothalamic Peptides: an Overview --; Chapter2 Analogs of Luteinizing Hormone-releasing Hormone in Benign Prostatic Hyperplasia and Advanced Renal Cell Carcinoma --; Chapter3 Luteinizing Hormone-releasing Hormone Antagonists in Gynecology --; Chapter4 Physiology and Pharmacology of Somatostatin and Its Receptors --; Chapter5 Investigation of LHRH Receptor Involvement in Melanoma Growth and Progression --; Somatostatin/GHRH/GH --; Chapter6 Cortistatin: Not Simply a Natural Somatostatin Analogue --; Chapter7 Antineoplastic and Antiangiogenic Actions of Somatostatin Analogs --; Chapter8 Somatostatin in Clinical Endocrinology --; Chapter9 Antagonists of Growth Hormone-releasing Hormone in Oncology --; Chapter10 GH Receptor Antagonists: Basic Knowledge and Clinical Perspectives --; Ghrelin and Ghrelin Mimetics (GHS) --; Chapter11 Hypothalamic Circuits Responsive to Ghrelin: Regulation by Leptin and Insulin --; Chapter12 Physiological Function of Growth Hormone Secretagogue Receptors in the Cardiovascular System --; Chapter13 Endocrine and Extraendocrine Activity of Ghrelin and the GHS: Basic Research --; Chapter14 Endocrine and Nonendocrine Actions of Ghrelin and GHS: State of the Art in Clinical Research --; Hormonal Treatments for Endocrine-Dependent Tumors --; Chapter15 Hormonal Treatments of Endocrine-Dependent Tumors: Preclinical Aspects --; Chapter16 Hormonal Treatment of Endocrine-Dependent Tumors: Clinical Considerations --; Chapter17 Letrozole in the Treatment of Advanced Breast Cancer.

Text of Note

The book describes the ability of a series of endocrine-derived compounds, i.e. CHRH, LHRH, somatostatin, anti-androgens, and aromatase inhibitors to exert a direct anti-neoplastic activity or to potentiate the activity of traditional chemotherapeutic agents on neuroendocrine and solid tumors. In addition, a new class of potent GH-releasers, GSHs/Ghrelin, endowed with important endocrine and extra-endcocrine action, is presented. Therefore, in addition to traditional chemotherapy, characterized by high toxicity and non-selective action on tumoral cells, the reader can find a new approach with more selective, less cytotoxic endocrine derived compounds.

Endocrinology.

Medicine.

Oncology.

Class number

Book number

edited by Eugenio E. Müller.

Eugenio E Müller

Electronic name

[Book]

Y