عنوان
پدید آورنده
موضوع
رده
RA1224.3 E339 2012
RA1224
.
3
E339
2012
کتابخانه
محل استقرار
INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
1849731772
(Number (ISBN
1849732922
(Number (ISBN
9781849731775
(Number (ISBN
9781849732925
NATIONAL BIBLIOGRAPHY NUMBER
Number
b587572
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
The cellular response to the genotoxic insult :
General Material Designation
[Book]
Other Title Information
the question of threshold for genotoxic carcinogens
First Statement of Responsibility
ed. by Helmut Greim ...
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Cambridge RSC Publishing
Date of Publication, Distribution, etc.
2012
SERIES
Series Title
Issues in toxicology, 13
GENERAL NOTES
Text of Note
Parallel als Buch-Ausg. erschienen
CONTENTS NOTE
Text of Note
Introduction: The rationale for thresholds for genotoxic carcinogens; Part 1. Threshold effects observed in experimental studies: Mechanisms responsible for the chromosome and gene mutations driving carcinogenesis: implications for dose-response characteristics of mutagenic carcinogens; Dose-effect relationships of DANN-reactive liver carcinogens; DNA alkylation and repair after EEMS exposure: Where do the thresholds for mutagenic/clastogenic effects arise? Part 2. Metabolic inactivation of genotoxic reactants: Enzymatic detoxification of endogenously produced mutagenic carcinogens maintaining cellular homeostasis; Phase 2 detoxifying enzymes and anti-oxygen defense mechanisms in the inactivation of genotoxic carcinogens; Part 3. DNA repair: Consequences and Repair of oxidative DNA damage; The plasticity of DNA damage response during cell differentiation: pathways and consequences; Tumor suppressor protein-mediated regulation of base excision repair in response to DNA damage; Part 4. Apoptosis: Survival and death strategies in cells exposed to genotoxin; Different modes of cell death induced by DNA damage; Transcriptional inhibition by DNA damage as a trigger of cell death; Part 5. Epigenetic mechanisms: The interplay between epigenetics and Gap junctionional intercellular communication; Index
LIBRARY OF CONGRESS CLASSIFICATION
Class number
RA1224
.
3
Book number
E339
2012
PERSONAL NAME - PRIMARY RESPONSIBILITY
ed. by Helmut Greim ...
PERSONAL NAME - ALTERNATIVE RESPONSIBILITY
Helmut Greim
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب [Book]
Y
