عنوان

Transition Metals in Biochemistry

(Number (ISBN

3540082913

(Number (ISBN

3642811485

(Number (ISBN

9783540082910

(Number (ISBN

9783642811487

Number

b574168

Title Proper

Transition Metals in Biochemistry

General Material Designation

[Book]

First Statement of Responsibility

by Arthur S. Brill.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1977

Specific Material Designation and Extent of Item

(viii, 186 pages 49 illustrations)

Series Title

Molecular biology, biochemistry, and biophysics, 26.

Text of Note

1 The Role of Transition Metal Ions in Biological Oxidation and Related Processes --; 1. Transition Metal Ions --; 2. Prosthetic Groups --; 3. Equilibrium Considerations in Reactions of Transition Metals --; 4. Molecular Functions of Proteins Containing Transition Metal Ion Prosthetic Groups --; 5. The Role Which a Transition Metal Ion Plays in the Function of a Protein --; 6. Experimental Methods --; 7. Some Aspects of the Role of the Polypeptide in the Functioning of Proteins Containing Transition Metal Ions --; 2 Metal Coordination in Proteins --; 1. Ligands --; 2. The Established Coordination in Several Proteins --; 3. Covalency --; 4. Some Aspects of Differences in Heme Binding --; 3 Copper --; 1. Cupric Peptides --; 2. EPR of Cupric Peptides and Related Complexes --; 3. The Blue Proteins --; 4. Magnetic and Optical Properties of Quantum Mechanical Models of the Cupric Ion --; 5. "Nonblue" Coordination in Copper Proteins --; 4 Heme Iron --; 1. Valence and Spin States of Iron --; 2. Magnetic Susceptibility --; 3. Valence State Determination --; 4. Optical Properties --; 5. Spin State Equilibria --; 6. Influences of Symmetry upon the Energy Levels of Low- and High-Spin States --; 7. Ligand Hyperfine Effects in Ferric Hemeproteins --; 8. Iron Hyperfine Effects --; 9. Modified Hemes --; 10. Photodissociation and Recombination --; 5 Nonheme Iron and Molybdenum --; 1. Iron Storage and Transport Proteins --; 2. Iron-Sulfur Proteins --; 3. Molybdenum --; 6 Electronic Structures and Properties --; 1. Atomic Orbitals --; 2. Spin States --; 3. Transition Metal Ions --; 4. Ligands and Molecular Orbitals --; 5. Absorption of Light --; 6. Interaction of Transition-Metal Ions with an Applied Magnetic Field --; 7. Magnetic Interactions of the Metal Electrons with Nuclei in the Coordination Sphere --; 8. Optical Activity --; References.

Text of Note

Transition metal ions in biological systems are of interest in biology, biochemistry, chemistry, medicine, and physics. Scien­ tists with rather different viewpoints, employing many methods, have contributed to this area. A concise review of the current state of the field will, to some extent, reflect the special knowledge of the person writing it - in this case application of physical methods to the investigation of metal coordination. x­ ray diffraction is one of the most important of these methods, but a useful treatment of X-ray structure analysis would be com­ parable in size with and beyond the scope of the monograph. Many results of X-ray diffraction studies are, of course, presented. Electron paramagnetic resonance spectroscopy has played a major part in the rapid advance in knowledge of the electronic struc­ tures of transition metal ions in biological systems. More gener­ ally, measurements involving light, microwaves, and magnetic fields are capable of producing much new information, and the required instrumentation is available at most research institu­ tions. Therefore light absorption and paramagnetic resonance are treated in depth. The principles described in the latter discus­ sions are broadly applicable, for example to the promising tech­ niques of X-ray spectroscopy (utilizing synchrotron radiation) and lanthanide-perturbed, very high-resolution nuclear magnetic resonance spectroscopy.

Life sciences.

Medicine.

Class number

Book number

by Arthur S. Brill.

Arthur S Brill

Electronic name

[Book]

Y