Modern Optics, Electronics and High Precision Techniques in Cell Biology
General Material Designation
[Book]
First Statement of Responsibility
edited by Gerhard Isenberg.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Berlin, Heidelberg
Name of Publisher, Distributor, etc.
Springer Berlin Heidelberg
Date of Publication, Distribution, etc.
1998
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
(viii, 261 pages 69 illustrations, 14 illustrations in color.)
SERIES
Series Title
Principles and practice.
CONTENTS NOTE
Text of Note
1 Atomic Force Microscopy Provides Molecular Details of Cell Surfaces --; 2 Basic Principles and Applications of Confocal Laser Scanning Microscopy --; 3 Visualization of Neuronal Form and Function in Brain Slices by Infrared Videomicroscopy --; 4 Time-Resolved Imaging of Membrane Potentials and Cytoplasmic Ions at the Cellular Level with a 50x50 Fiber Array Photodiode Camera --; 5 Micromanipulation of Macromolecules: How to Measure the Stiffness of Single Microtubules --; 6 Dynamics of Single Protein Polymers Visualized by Fluorescence Microscopy --; 7 The Interaction of Proteins with Membrane Surfaces at Molecular Resolution: The Neutron Reflection Method --; 8 The Study of Fast Reactions by the Stopped-Flow Method --; 9 Biomolecular Interactions Analysis (BIA Technology). A Universal Biosensor-Based Technology for Biochemical Research and Development --; 10 Measuring Cellular Locomotion Forces with Micro-Machined Substrates --; 11 Viscoelasticity, Rheology and Molecular Conformational Dynamics of Entangled and Cross-Linked Actin Networks.
SUMMARY OR ABSTRACT
Text of Note
The techniques described in this book provide an alternative method to understanding cellular biological structures and processes. Molecular genetic methods mainly analyse single molecules or very small cellular parts, which does not necessarily enhance our understanding of the fundamental cellular processes. However, using techniques such as atomic force or infrared microscopy, neutron reflection, stopped-flow cytometry, laser microscopy, or biosensoric-based electronics, it is possible to study cells and biological systems in their entirety. Physiological processes of cells, such as movement, development, plasticity, regeneration and communication, can be visualized using the high precision biophysical techniques described here.