عنوان

The Endothelins

(Number (ISBN

3540528563

(Number (ISBN

364275872X

(Number (ISBN

9783540528562

(Number (ISBN

9783642758720

Number

b573442

Title Proper

The Endothelins

General Material Designation

[Book]

First Statement of Responsibility

by Winifred G. Nayler.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1990

Specific Material Designation and Extent of Item

(xiii, 183 pages 69 illustrations)

Text of Note

1 The Discovery and General Properties of the Endothelins --; 2 The Chemistry of the Endothelins --; 3 The Biosynthesis of the Endothelins --; 4 Other Chemically-Related Toxins --; 5 The Contractile Effect of Endothelin-1 --; 6 The Biochemical Events Involved in the Contractile and Positive Inotropic Activity of Endothelin-1 --; 7 Endothelin Receptors: Their Distribution and Properties --; 8 Metabolism and Clearance of the Endothelins --; 9 Plasma, Tissue and Urine Endothelin-1 --; 10 Effect of Various Pathological Conditions on Plasma Endothelin --; 11 Endothelin and the Kidney --; 12 Endothelin and the Brain --; 13 Endothelin and the Coronary Circulation --; 14 Endothelin-1 and the Heart --; 15 Endothelin, Cell Proliferation and Atherosclerosis --; 16 The Constrictor Effect of the Endothelins on Bronchiolar and Tracheal Smooth Muscle --; 17 Endothelin and Hypertension --; 18 The Endothelins and Platelet Aggregation --; 19 Do the Endothelins have a Future? --; References.

Text of Note

This book has been written to provide a factual account of the history, chemistry, and physiological and pathological importance of the endothelin family of polypeptides. These polypeptides are a very recent discovery and their true significance is still being established. However, they are of enormous potential significance, particularly with respect to the functioning of the circulatory system under normal and abnormal conditions. The reader's attention therefore is directed towards the possible involvement of these polypeptides in the aetiology of ischaemic heart disease, cerebrovascular accidents, hypertension, atherosclerosis and renal failure. This book represents the first attempt to draw together data which is currently available concerning the endothelins, and as such it provides a fascinating insight into a new and novel area of research. It aims to provide a documented account of the history and significance of these polypeptides and hence opens up new areas of future research.

Cardiology.

Human physiology.

Medicine.

Class number

Book number

by Winifred G. Nayler.

Winifred G Nayler

Electronic name

[Book]

Y