عنوان

Drugs for the Treatment of Parkinson's Disease

(Number (ISBN

3540500413

(Number (ISBN

3642738990

(Number (ISBN

9783540500414

(Number (ISBN

9783642738999

Number

b573220

Title Proper

Drugs for the Treatment of Parkinson's Disease

General Material Designation

[Book]

First Statement of Responsibility

edited by Donald B. Calne.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1989

Specific Material Designation and Extent of Item

(xxiv, 599 pages 62 illustrations)

Series Title

Handbook of experimental pharmacology, 88.

Text of Note

1 Neurophysiology of Basal Ganglia --; 2 Pathology of Parkinson's Syndrome --; 3 Biochemical Neuroanatomy of the Basal Ganglia --; 4 Receptors in the Basal Ganglia --; 5 Imaging the Basal Ganglia --; 6 The Neurochemical Basis of the Pharmacology of Parkinson's Disease --; 7 Pyridine Toxins --; 8 The Relationship Between Parkinson's Disease and Other Movement Disorders --; 9 Evaluation of Parkinson's Disease --; 10 Clinical Trials for Parkinson's Disease --; 11 Experimental Therapeutics Directed at the Pathogenesis of Parkinson's Disease --; 12 Anticholinergic Drugs and Amantadine in the Treatment of Parkinson's Disease --; 13 The Pharmacology of Levodopa in Treatment of Parkinson's Disease: An Update --; 14 Adverse Effects of Levodopa in Parkinson's Disease --; 15 Monoamine Oxidase Inhibitors in Parkinson's Disease --; 16 Clinical Actions of l-Deprenyl in Parkinson's Disease --; 17 Update on Bromocriptine in Parkinson's Disease --; 18 Pergolide in the Treatment of Parkinson's Disease --; 19 Lisuride Pharmacology and Treatment of Parkinson's Disease --; 20 Domperidone and Parkinson's Disease --; 21 New Routes of Administration for Antiparkinsonian Therapy --; 22 Treatment of Parkinsonian Features in Neurological Disorders Other than Parkinson's Disease --; 23 Management of Psychiatric Symptoms in Parkinson's Disease --; 24 Intracranial grafts for the treatment of Parkinson's Disease.

Text of Note

This volume provides a comprehensive reference on drugs employed to treat Parkinson's disease. Since pharmacology is dependent upon physiology, and physiology upon anatomy, the multiauthored contents build up from all these disciplines to applied therapeutics. Our knowledge of synaptic mechanisms in the striatum is reviewed; and drugs are considered as therapeutic tools to manipulate synaptic function. Methods of evaluating treatment in Parkinson's disease are discussed in order to provide a background against which the reader can determine whether therapeutic studies are meaningful. The volume deals with old drugs (anticholinergic agents), conventional drugs (levodopa and decarboxylase inhibitors) and new drugs (dopamine agonists). Drugs designed to modify the natural history of Parkinson's disease (antioxidants) are reviewed, and drugs employed to reduce adverse reactions are discussed (extracerebral D2 antagonists). Novel routes for administering drugs are included (parenteral infusions) and finally, current approaches to transplanting dopaminergic cells into the striatum are summarized. This book is intended to meet the needs of physicians who treat Parkinson's disease, to assist pharmacologists who are concerned with the development of improved methods for controlling symptoms, and to stimulate those neurobiologists who have an interest in attempting to slow down the inexorable progress of the disorder.

Parallel Title

With contributions by numerous experts

Medicine.

Neurosciences.

Toxicology.

Class number

Book number

edited by Donald B. Calne.

Donald B Calne

Electronic name

[Book]

Y