Current topics in microbiology and immunology, 227.
CONTENTS NOTE
Text of Note
List of Contents --; Cyclin-Dependent Kinase Inhibitors of Saccharomyces cerevisiae and Schizosaccharomyces pombe --; Inhibitors of the Cip/Kip Family --; The INK4 Family of CDK Inhibitors --; Role of Cyclin-Dependent Kinases and Their Inhibitors in Cellular Differentiation and Development --; Roles of Cyclin-Dependent Kinase Inhibitors: Lessons from Knockout Mice --; p21/p53, Cellular Growth Control and Genomic Integrity --; Cyclin-Dependent Kinase Inhibitors and Human Cancer --; Small-Molecule Inhibitors of Cyclin-Dependent Kinases: Molecular Tools and Potential Therapeutics.
SUMMARY OR ABSTRACT
Text of Note
This volume constitutes a comprehensive collection of acticles on cyclin-dependent kinase inhibitors. The topics covered range from the basic biology and biochemistry of these proteins to their roles in development and carcinogensis. All the organisms where cyclin-dependent kinase inhibitors have been intensively studied, including yeast, mouse and man, are represented in the discussion. All of the articles have been contributed by experts in their respective discipline and provide up-to-date views of the field from the perspective of working scientists. As this is the first comprehensive volume strictly dedicated to the topics CDK inhibitors, it will be a valuable resource for anyone who needs or wishes to familiarize themselves with current thought on cell cycle regulation.