Interactions with Testosterone and Cortisol in Cardiovascular Diseases
First Statement of Responsibility
by Jens Møller.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Berlin, Heidelberg
Name of Publisher, Distributor, etc.
Springer Berlin Heidelberg
Date of Publication, Distribution, etc.
1987
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
(16 illustrations)
CONTENTS NOTE
Text of Note
Cholesterol --; Testosterone in the Maintenance of Life --; Biochemical Relations Between Cholesterol, Testosterone, Cortisol, and Catecholamines --; Fat Burns in the Flame of Carbohydrate --; Free Fatty Acid Metabolism --; The Nature of Cardiovascular Disease --; Difficulty in Distinguishing Ageing and Pathological Processes --; pH as a Variable in Metabolism --; Stress --; Infarction Due to Metabolic Processes Other than Vessel Occlusion --; Testosterone as an Alternative to Surgery for CVD --; Peripheral Vascular Disease --; Diabetic States and CVD --; Use of Anabolic Steroids in Surgical Stress --; Increasing Testosterone and Decreasing Cholesterol by Physical Training --; The Negative Nitrogen Balance --; Effect of Negative Nitrogen Balance --; Excess of Cortisol --; Administration of Testosterone --; Evaluation of the Parameters of CVD --; Further Comments on Evaluation of Parameters --; Comments on Photographs --; The Balance Between Hormone Sensitive Lipase and Postheparin Lipoprotein Lipase --; Treatment of CVD with Testosterone --; The Ultimate Involution of the Biological Functions --; Conclusion --; Exchange of Views on the Themes of the Book --; Discussion with Malcolm Carruthers --; Action Now on Circulatory Disease by M. Carruthers --; Discussion with Gunde Egeskov Jensen --; Epilogue --; Publications Dealing with the Effect of Testosterone on the Parameters of CVD --; References.
SUMMARY OR ABSTRACT
Text of Note
In 1935, Butenandt and Ruzicka received the Nobel Prize for synthesizing testosterone from cholesterol. Over the next few years, testosterone was used therapeutically by several clinicians, especially in Germany. However, with the outbreak of the Second World War, international scientific research was effectively brought to an end. Using testosterone extracted from postmortem material, workers at the clinic of the famous Danish surgeon Thorkild Rovsing were able to show as early as the First World War that the substance had beneficial effects on cardiovascular disease. Given that this particularly important chapter in medical history opened in Copenhagen, it is appropriate that testosterone treatment was taken up in the 1950s by Jens Meller. During the 35 years since then, he has gained enormous experience in treating cardiovascular disease and is amply qualified to review the role testosterone has played in the more than ten thousand patients he has treated, most of them successfully. Many have even been saved the experience of amputation. Drawing on authoritative sources and expert opinion in the fields of biochemistry and physiology, this book explains the scientific basis that underlies this achievement. It is a success I have seen personally in the course of several periods spent working with Meller in Copenhagen.