New Attitudes to Experimental Teratology --; 1. A Developmental Approach to Teratology --; 2. Chromosomal Animal Model of Human Disease. Fetal Trisomy and Developmental Failure --; 3. Animal Models of Major Gene Defects --; 4. Cytotoxic Agents in Teratogenic Research --; Problems of Predictive Teratology --; 5. Polygenic Models in Teratological Testing --; 6. Behavioural Teratology --; 7. Teratological Investigations in Laboratory Primates: Why, When and How to Use Them --; 8. Screening Medicines for Teratogenicity: Problems of Interpretation --; Influencing the Fetal Milieu --; 9. Placental Causes of Maldevelopment --; 10. Future Prospects for Fetal Surgery --; New Aspects of Developmental Teratology --; 11. Morphological and Behavioural Abnormalities Caused by Insults to the CNS in the Perinatal Period --; 12. Polymorphisms: Their Lessons for Human Teratology --; 13. The Impact of Malformation on the Emotional Development of the Child and his Family.
SUMMARY OR ABSTRACT
Text of Note
In the fifteen years since the thalidomide disaster teratology has become a science in its own right, distinct from its progenitors, experimental embryology and develop mental biology, but bearing many of the familiar features of both parents. In this growth period there have been contributions from many different scientific disciplines as diverse as molecular biology and obstetrics, which have united in the field of study of congenital malformations. Scientists in academic departments, government research institutes and industrial pharmacology have all explored ways of evaluating the potenti.