عنوان

The Biochemistry of Alkaloids

(Number (ISBN

3642618308

(Number (ISBN

3642618324

(Number (ISBN

9783642618307

(Number (ISBN

9783642618321

Number

b571864

Title Proper

The Biochemistry of Alkaloids

General Material Designation

[Book]

First Statement of Responsibility

by Trevor Robinson.

Edition Statement

Second edition

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1981

Series Title

Molecular biology, biochemistry, and biophysics, 3.

Text of Note

1 Introduction --; 2 General Theories of Alkaloid Biosynthesis --; 3 Simple Amino Acid Derivatives and Protoalkaloids --; 4 Pyrrolidine, Piperidine, and Pyridine Alkaloids --; Pyrrolidine Alkaloids --; Piperidine Alkaloids --; Pyridine Alkaloids --; Trigonelline and Other Simple Derivatives of Nicotinic Acid --; Ricinine --; Tobacco Alkaloids --; Nicotinic Acid --; 5 Tropane Alkaloids --; 6 Lupine Alkaloids --; 7 Isoquinoline Alkaloids --; 8 Aporphine and Morphinan Alkaloids --; 9 Amaryllidaceae Alkaloids and Colchicine --; 10 Indole Alkaloids --; Ergot Alkaloids --; 11 Quinolines and Other Alkaloids Related to Anthranilic Acid --; 12 Some Miscellaneous Alkaloids --; Pyrrolizidine Alkaloids --; Purine Alkaloids --; Benzoxazoles --; Betalains --; Imidazole Alkaloids --; 13 Terpenoid and Steroid Alkaloids --; Diterpenoids and Triterpenoids --; Steroids --; 14 Metabolism of Exogenous Alkaloids --; Animals --; Microorganisms --; Higher Plants --; 15 Biochemical Effects of Alkaloids --; Cholinergic and Adrenergic Systems --; The Opiate Recepter --; Serotonin Receptors --; Miscellaneous Membrane Receptors --; Ion Transport and Membrane Permeability --; Metabolic Effects --; Effects on Nucleic Acids and Protein Synthesis --; Mitosis Inhibitors.

Text of Note

The alkaloids were of great importance to mankind for centuries, long before they were recognized . as a chemical class. The influence they have had on literature is hinted at by some of the quotations I have used as chapter headings. Their influence on folklore and on medicine has been even greater. The scientific study of alkaloids may be said to have begun with the isolation of morphine by Sertiirner in 1804. Since that time they have remained of great interest to chemists, and now in any month there appear dozens of publications dealing with the isolation of new alkaloids or the determination of the structures of previously known ones. The area of alkaloid biochemistry, in comparison, has received little attention and today is much less developed. There is a certain amount of personal arbitrariness in defining "bio­ chemistry", as there is in defining "alkaloid", and this arbitrariness is doubtless compounded by the combination. Nevertheless, it seems to me that in any consideration of the biochemistry of a group of compounds three aspects are always worthy of attention-pathways of biosynthesis, function or activity, and pathways of degradation. For the alkaloids, treatment of these three aspects is necessarily lopsided. Much has been learned about routes of biosynthesis, but information on the other aspects is very scanty. It would be possible to enter into some speculation regarding the biosynthesis of all the more than 4,000 known alkaloids.

Biochemistry.

Life sciences.

by Trevor Robinson.

Trevor Robinson

Electronic name

[Book]

Y