عنوان

Vitamin D Analogs in Cancer Prevention and Therapy

(Number (ISBN

3642555802

(Number (ISBN

9783642555800

Number

b570128

Title Proper

Vitamin D Analogs in Cancer Prevention and Therapy

General Material Designation

[Book]

First Statement of Responsibility

edited by Jörg Reichrath, Wolfgang Tilgen, Michael Friedrich.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

2003

Specific Material Designation and Extent of Item

(viii, 432 pages)

Series Title

Recent results in cancer research, 164.

Text of Note

From the contents: Molecular Biology of Vitamin D: Evolution and function of vitamin D. Evaluating the association of vitamin D receptor gene polymorphisms with breast cancer risk. Ligand structure-function relationships in the vitamin D endocrine system. Mechanisms implicated in the growth regulatory effects of vitamin D compounds in breast cancer cells. A novel vitamin D-regulated immediate early gene, IEX-1, alters cellular growth and apoptosis --; The Vitamin D System in Cancer: The role of vitamin D in prostate cancer. Vitamin D autocrine system and prostate cancer. Analysis of the vitamin D system in cervical carcinomas, breast and ovarian cancer. Analysis of the vitamin D system in cutaneous malignancies --; Antitumor Effects of Vitamin D Analogs: Evaluation of vitamin D analogs as therapeutic agents for prostate cancer. Induction of apoptosis by vitamin D metabolites and analogs in a glioma cell line. Vitamin D analogs and breast cancer --; Vitamin D in Cancer Prevention: Ecologic studies of solar UV-B radiation and cancer mortality rates. Regulation of extrarenal vitamin D metabolism as a tool for colon and prostate cancer prevention.

Text of Note

This volume provides a comprehensive, highly readable overview of the topics discussed at the First International Symposium on "Vitamin D Analogs in Cancer Prevention and Therapy" held in Homburg/Saar, Germany in May 2002. Leading researchers discuss our present knowledge of the vitamin D system in cancer. Topics range from the newest findings in molecular biology, epidemiology, synthesis and metabolism of vitamin D to new concepts for the use of vitamin D analogs in cancer prophylaxis and treatment. The book provides essential up-to-date information for every researcher or clinician interested in the biology of vitamin D or cancer.

Medicine.

Neoplasms -- drug therapy.

Oncology.

edited by Jörg Reichrath, Wolfgang Tilgen, Michael Friedrich.

Jörg Reichrath

Michael Friedrich

Wolfgang Tilgen

Electronic name

[Book]

Y