(XIV, 254 pages 21 illustrations, 7 illustrations in color.)
SERIES
Series Title
Current topics in microbiology and immunology, 278.
CONTENTS NOTE
Text of Note
Genetic modification of xenografts --; Public health risks --; patient versus society in an emerging field --; Cross-species infections --; Non-human primate herpesviruses: importance for xenotransplantation --; Understanding xenotransplantation risks from non-swine hepatitis E virus: cross-species infection and risk in xenotransplantation --; Molecular cloning and functions characterization of infectious PERV and development of diagnostic tests --; Xenotransplantation --; Federal regulatory considerations --; Subject index.
SUMMARY OR ABSTRACT
Text of Note
Xenotransplantation could have an impact on at least three aspects of medicine. The first is as a means of overcoming a severe shortage of human donor organs for the treatment of organ failure. The second aspect relates to the possibility that a xenogeneic organ would not be susceptible to infection by a "human" virus and thus the xenograft might resist injury caused by such viruses. The third and, as of yet, unexplored aspect relates to a means of delivering genes for therapeutic purposes thus overcoming some of the limitations of "conventional" gene therapy.