Current topics in microbiology and immunology, 174.
CONTENTS NOTE
Text of Note
Molecular Genetics of Pyrogenic Exotoxin "Superantigens" of Group A Streptococci and Staphylococcus aureus --; T Cell Recognition of Superantigens --; T Cell Activation by Superantigens--Dependence on MHC Class II Molecules --; The Human T Cell Response to Mitogenic Microbial Exotoxins --; Toxic Shock Syndrome Toxin-1, Toxic Shock, and the Immune System --; Staphylococcal Enterotoxin-Dependent Cell-Mediated Cytotoxicity --; CD4/CD8 Coreceptor-Independent Costimulator-Dependent Triggering of SEB-Reactive Murine T Cells --; The Immunobiology of Mycoplasma arthritidis and its Superantigen MAM --; The Anti-CD3-Induced Syndrome: A Consequence of Massive In Vivo Cell Activation.
SUMMARY OR ABSTRACT
Text of Note
This volume is concerned with "superantigens", a class of molocules that areknown to be the most potent stimulators of T lymphocytes. Prototypes are theenterotoxins and the toxic-shock-syndrome toxin produced by Staphylococcus aureus. The chapters discuss the molecular biology and genetics of different superantigens and their biological and clinical significance.