عنوان

Aminoglycoside Antibiotics

(Number (ISBN

364268579X

(Number (ISBN

3642685811

(Number (ISBN

9783642685798

(Number (ISBN

9783642685811

Number

b558346

Title Proper

Aminoglycoside Antibiotics

General Material Designation

[Book]

First Statement of Responsibility

edited by Hamao Umezawa, Irving R. Hooper.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1982

Series Title

Handbook of Experimental Pharmacology, Continuation of Handbuch der experimentellen Pharmakologie,, 62.

Text of Note

1 The Naturally Occurring Aminoglycoside Antibiotics --;A. Introduction --;B. Aminoglycoses and Noncyclitol Aminoglycosides --;C. Aminocyclitol Aminoglycosides Containing Streptamine, 2-Deoxystreptamine, or Their Derivatives --;D. Aminoglycosides with Cyclitol Aglycones Other than Streptamine or 2-Deoxystreptamine --;References --;2 Total Synthesis and Chemical Modification of the Aminoglycoside Antibiotics --;A. Introduction --;B. Several Reactions and Methods Generally Useful for the Synthesis of Aminoglycoside Antibiotics --;C. Total Synthesis and Modification of Aminoglycoside Antibiotics --;References --;3 Biosynthesis and Mutasynthesis of Aminoglycoside Antibiotics --;A. Introduction --;B. Biosynthesis of Major Aminoglycosides --;C. Mutational Biosynthesis (Mutasynthesis) --;D. Conclusion --;References --;4 Antibacterial Activity of Aminoglycoside Antibiotics --;A. Introduction --;B. Drug Resistance Plasmids --;C. Resistance Patterns of Bacteria --;D. Bacterial Strains Resistant to Aminoglycoside Antibiotics --;E. Conclusion --;References --;5 Mechanism of Action of Aminoglycoside Antibiotics --;A. The Effects on Bacterial Cells and Their Components --;B. Effects on Mammalian or Eukaryotic Cells and Their Components --;C. Peptide Antibiotics Showing Similar Mechanisms of Inhibition of Ribosomal Functions --;D. Discussion --;E. Summary --;References --;6 Mechanisms of Resistance to Aminoglycoside Antibiotics --;A. Introduction --;B. Biochemical Mechanisms of Resistance --;C. Derivatives Active Against Resistant Strains --;D. Conclusion --;References --;7 Toxicology and Pharmacology of Aminoglycoside Antibiotics --;A. Introduction --;B. Nephrotoxicity of Aminoglycosides --;C. Ototoxicity of Aminoglycosides --;D. Acute Lethal Toxicity of Aminoglycosides --;E. Correlation Between Chemical Structure and LD50 Values of Aminoglycosides --;F. General Pharmacology of Aminoglycosides --;G. Pharmacokinetics --;References.

Parallel Title

With contributions by numerous experts

Medicine.

Pharmacy.

Toxicology.

edited by Hamao Umezawa, Irving R. Hooper.

Hamao Umezawa

Irving R Hooper

Electronic name

[Book]

Y