Front Cover"; "Crash Course: Pathology"; "Copyright"; "Series editor foreword"; "Prefaces"; "Acknowledgements"; "Dedication"; "Contents"; "Part I: Principles of pathology"; "Chapter 1: Introduction to pathology"; "Diseases"; "Pathology"; "Divisions of pathology"; "Classification of disease"; "Congenital"; "Acquired"; "How pathology is covered in this book"; "Part I: Principles of pathology"; "Part II: Systematic pathology"; "Chapter 2: Inflammation, repair and cell death"; "Inflammation"; "Definition"; "Purpose"; "Causes of acute inflammation" "Causes of chronic inflammation""Acute inflammation"; "Classic signs of acute inflammation"; "Vascular response"; "Vasodilatation"; "Increased vascular permeability"; "Inflammatory oedema"; "Advantages of inflammatory oedema"; "Cellular events"; "Phagocytosis and intracellular killing"; "Chemical mediators of inflammation"; "The complement system"; "Kinins"; "Arachidonic acid, prostaglandins and leukotrienes"; "Platelet activation factors"; "Vasoactive amines"; "Cytokines"; "Nitric oxide"; "Acute-phase proteins"; "Chronic inflammation" "Mononuclear infiltration and granulation tissue""Wound healing"; "Nature of cells"; "1. Healing by first intention"; "2. Healing by second intention"; "Scar formation"; "Patterns of inflammation"; "Fibrinous inflammation"; "Suppurative inflammation"; "Haemorrhagic inflammation"; "Granulomatous inflammation"; "Systemic effects of inflammation"; "Cell death"; "Mechanisms of cell death"; "Necrosis"; "Histological types of necrosis"; "Coagulative necrosis"; "Liquefactive necrosis"; "Caseous necrosis (caseation)"; "Fibrinoid necrosis"; "Fat necrosis" "Apoptosis""Mechanisms of apoptosis"; "Chapter 3: Cancer"; "Definitions and nomenclature"; "Definitions"; "Tumour"; "Dysplasia"; "Metaplasia"; "Hyperplasia"; "Hypertrophy"; "Benign versus malignant"; "Nomenclature of tumours"; "Classification of carcinomas"; "Intraepithelial neoplasia"; "Carcinoma in situ"; "Invasive carcinoma"; "Epidemiological aspects of cancer"; "Cancer in the UK"; "Cancer worldwide"; "Molecular basis of cancer"; "Oncogenes and tumour suppressor genes"; "Proto-oncogenes"; "Tumour suppressor genes" "Multistage model of tumour progression""Tumour growth and spread"; "Kinetics of tumour growth and angiogenesis"; "Mechanisms and pathways of invasion and metastasis"; "Invasion"; "Metastasis"; "Main routes of metastasis"; "Carcinogenic agents"; "Chemical carcinogens"; "Stages of chemical carcinogenesis"; "Radiation"; "Ultraviolet radiation"; "Ionizing radiation"; "X-ray radiation"; "Radioisotopes"; "Nuclear radiation"; "DNA repair mechanisms and their failure"; "Viruses"; "Mechanism of viral carcinogenesis"; "Host defences against cancer"
SUMMARY OR ABSTRACT
Text of Note
Authored by students or junior doctors - working under close faculty supervision, this title begins with 'Learning Objectives'. Each chapter guides you succinctly through the topic, giving full coverage of the curriculum whilst avoiding unnecessary and often confusing detail. It also features 'Hints and Tips' boxes and other useful aide-memoires.