I: ATP: The Molecule --;1 ATP and the heart: An overview --;2 The basics --;3 The chemistry of the ATPase reaction --;4 Ways to measure ATP and related metabolites --;II: ATP: Degradation Pathway and de novo Synthesis --;5 Degradation and synthesis of ATP --;III: ATP Utilizing Pathways --;6 The work of contraction: Myosin ATPase --;7 The work of ion movements --;8 The work of macromolecular synthesis and degradation --;IV: ATP Synthesizing Pathways --;9 ATP synthesis pathways: glycolysis --;10 ATP synthesis pathways: oxidative phosphorylation --;11 ATP synthesis pathways: phosphotransferase reactions --;V: ATP and the Heart --;12 Integration of ATP synthesis and ATP utilization pathways.
SUMMARY OR ABSTRACT
Text of Note
New insights into ATP have been gleaned using biophysical techniques allowing dynamic measurement of chemical events in the intact beating heart and using new animal models in which cardiac proteins are either over expressed, deleted or harbor specific mutations.