عنوان

Aging methods and protocols

(Number (ISBN

0585344183

(Number (ISBN

1280820616

(Number (ISBN

1592590705

(Number (ISBN

6610820619

(Number (ISBN

9780585344188

(Number (ISBN

9781280820618

(Number (ISBN

9781592590704

(Number (ISBN

9786610820610

Number

b553206

Title Proper

Aging methods and protocols

General Material Designation

[Book]

First Statement of Responsibility

edited by Yvonne A. Barnett, Christopher R. Barnett.

Place of Publication, Distribution, etc.

Totowa, NJ

Name of Publisher, Distributor, etc.

Humana Press

Date of Publication, Distribution, etc.

©2000.

Specific Material Designation and Extent of Item

(xiv, 385 pages) : illustrations

Series Title

Methods in molecular medicine, 38.

Text of Note

1. Understanding Aging / Bernard L. Strehler --;pt. I. Study of Cell Senescence and Cell Death --;2. Use of the Fibroblast Model in the Study of Cellular Senescence / Vincent J. Cristofalo, Craig Volker and Robert G. Allen --;3. Human T-Cell Clones / Graham Pawelec --;4. Telomeres and Replicative Senescence / Hector F. Valenzuela and Rita B. Effros --;5. Detection of Molecular Events During Apoptosis by Flow Cytometry / Ruaidhri J. Carmody, Ana P. Costa-Pereira, Sharon L. McKenna, and Tom G. Cotter --;6. Raf-1 Protein Kinase Activity in T Cells from Aged Mice / Christopher J. Kirk and Richard A. Miller --;7. Identification of Differentially Expressed Genes in Young and Senescent T Cells / Andrea Engel, Mahdi Adibzadeh and Graham Pawelec --;pt. II. Age-Related Changes to Xenobiotic Metabolizing Enzyme Systems --;8. Xenobiotic-Metabolizing Enzyme Systems and Aging / Christopher R. Barnett and Costas Ioannides --;pt. III. Age-Related Changes to Defense Systems Against Biomolecule Damage --;9. Assessing Age-Related Changes in Antioxidant Status: The FRASC Assay for Total Antioxidant Power and Ascorbic Acid Concentration in Biological Fluids / Iris F.F. Benzie and John J. Strain --;10. Measurement of DNA Damage and Repair Capacity as a Function of Age Using the Comet Assay / Peter H. Clingen, Jillian E. Lowe and Michael H.L. Green --;11. Measurement of DNA Damage and Repair in Human White Blood Cells by an Immunochemical Assay / Govert P. van der Schans --;pt. IV. Age-Related Changes to Cellular Biomolecules --;12. Measurement of 8-Oxo-deoxyguanosine in Lymphocytes, Cultured Cells, and Tissue Samples by HPLC with Electrochemical Detection / Sharon G. Wood, Catherine M. Gedik, Nicholas J. Vaughan, and Andrew R. Collins --;13. Mutation and the Aging Process: Mutant Frequency at the HPRT Gene Locus as a Function of Age in Humans / Yvonne A. Barnett and Christopher R. Barnett --;14. Somatic Mutations and Aging: Methods for Molecular Analysis of HPRT Mutations / Sai-Mei Hou --;15. Assessment of Susceptibility of Low-Density Lipoprotein to Oxidation / Jane McEneny and Ian S. Young --;16. Measurement of Pentosidine in Biological Samples / Jesus R. Requena, David L. Price, Suzanne R. Thorpe, and John W. Baynes --;pt. V. Mitochondrial Morphology, Function and Mutation with Age --;17. Causes and Consequences of Damage to Mitochondria: Morphological Aspects / Jaime Miquel and Carlo Bertoni-Freddari --;18. Causes and Consequences of Damage to Mitochondria: Study of Functional Aspects by Flow Cytometry / Federico V. Pallardo, Juan Sastre, Jaime Miquel, and José Viña --;19. Analysis of Mitochondrial DNA Mutations: Deletions / Robert W. Taylor, Theresa M. Wardell, Emma L. Blakely, Gillian M. Borthwick, Elizabeth J. Brierley, and Douglass M. Turnbull --;20. Analysis of Mitochondrial DNA Mutations: Point Mutations / Robert W. Taylor, Richard M. Andrews, Patrick F. Chinnery, and Douglass M. Turnbull --;pt. VI. Immune System and Aging --;21. Assessment of T-Cell Function in the Aged: T-Cell Proliferative and T-Cell Adherence Assays / Ian Beckman --;22. Dendritic Cells in Old Age / Beatrix Grubeck-Loebenstein, Maria Saurwein-Teissl and Nikolaus Romani --;23. Age-Related Alterations to Natural Killer Cell Function / Erminia Mariani, Corona Alonso and Rafael Solana --;24. Immunogenetics and Life-Span: HLA / Derek Middleton, Martin D. Curran and Fionnuala Williams --;pt. VII. Case Studies --;25. Dietary Restriction and Life-Span Extension / Byung Pal Yu --;26. Use of Genetically Engineered Mice in Aging Research / Julie K. Andersen.

Text of Note

Aging is an almost universal process within biological systems, one which leads to a decline in functional capacity, disease onset, and eventually death.

Aging -- Molecular aspects -- Laboratory manuals.

Aging.

Research Design.

Class number

Book number

edited by Yvonne A. Barnett, Christopher R. Barnett.

Christopher R Barnett

Yvonne A Barnett

Electronic name

[Book]

Y