عنوان

G proteins, receptors, and disease

(Number (ISBN

1461218020

(Number (ISBN

1461272904

(Number (ISBN

9781461218029

(Number (ISBN

9781461272908

Number

b550499

Title Proper

G proteins, receptors, and disease

General Material Designation

[Book]

First Statement of Responsibility

edited by Allen M. Spiegel.

Place of Publication, Distribution, etc.

Totowa, N.J.

Name of Publisher, Distributor, etc.

Humana Press

Date of Publication, Distribution, etc.

©1998.

Specific Material Designation and Extent of Item

(x, 324 pages) : illustrations (some color).

Series Title

Contemporary endocrinology (Totowa, N.J.), 6.

Text of Note

1 Introduction to G-Protein-Coupled Signal Transduction and Human Disease --;2 Albright Hereditary Osteodystrophy, Pseudohypopara-thyroidism, and Gs Deficiency --;3 Gas-Activating Mutations: A Cause of Acromegaly, Thyroid Adenomas, Fibrous Dysplasia, and the McCune-Albright Syndrome --;4 Ulcerative Colitis in Mice Lacking G?i2 --;5 G Proteins Regulating Insulin Action and Obesity: Analysis by Conditional, Targeted Expression of Antisense RNA in vivo --;6 G;12- and G?3- Subunits of Heterotrimeric G Proteins : A Novel Family of Oncogenes --;7 Hypo- and Hyperthyroidism Caused by Mutations of the TSH Receptor --;8 Disorders Caused by Mutations of the Lutropin/ Choriogonadotropin Receptor Gene --;9 Inactivating and Activating Mutations of the FSH Receptor Gene --;10 Nephrogenic Diabetes Insipidus and Vasopressin Receptor Mutations --;11 Disorders with Increased or Decreased Responsiveness to Extracellular Ca2+ Owing to Mutations in the Ca2+0-Sensing Receptor --;12 Constitutively Active PTH/PTHrP Receptors Cause Jansen's Metaphyseal Chondrodysplasia --;13 Mutation of the Growth Hormone-Releasing Hormone Receptor in the little Mouse --;14 Functional Variants of the MSH Receptor (MC1-R), Agouti, and Their Effects on Mammalian Pigmentation --;15 ACTH Resistance Syndromes --;16 Altering Adrenergic Signaling and Cardiac Function in Transgenic Mice --;17 Dopamine Receptors in Human Disease: Lessons from Targeted Mouse Mutants --;18 The?3-Adrenergic Receptor and Susceptibility to Obesity, the Insulin Resistance Syndrome, and Noninsulin-Dependent Diabetes Mellitus.

Text of Note

This collection summarizes in-depth the state of knowledge concerning how cells communicate via G-protein-coupled signal transduction and how defects in these proteins and their receptors can cause serious human disease involving many different organ systems.

Endocrine glands -- Diseases.

G proteins -- Pathophysiology.

G proteins -- Physiological effect.

Class number

Book number

edited by Allen M. Spiegel.

Allen M Spiegel

Electronic name

[Book]

Y