I. General Remarks.- II. Anatomy.- 1. Lips (Upper and Lower).- 2. Buccal Mucosa.- 3. Lower Alveolar Ridge.- 4. Upper Alveolar Ridge.- 5. Retromolar Gingiva (Retromolar Trigone).- 6. Floor of the Mouth.- 7. Hard Palate.- 8. Anterior Two-Thirds of the Tongue.- III. Purpose.- References.- 1. Etiology and Epidemiology.- I. Overview.- II. Possible Predisposing Factors.- 1. Tobacco.- 2. Radiation.- 3. Nutritional Factors.- 4. Alcohol.- 5. Genetic Susceptibility.- 6. Viruses.- 7. Syphilis.- 8. Traumatic Irritation.- III. Oral Precancerous Conditions.- 1. Leukoplakia.- 2. Erythroplakia.- 3. Submucous Fibrosis.- IV. Epidemiology.- References.- 2. Detection.- I. Oral Examination.- 1. Facial Structure.- 2. Lymph Nodes.- 3. Temporomandibular Joint.- 4. Lips.- 5. Vestibules and Frenums.- 6. Gingivae.- 7. Buccal Mucosa and Commissures.- 8. Tongue.- 9. Floor of the Mouth.- 10. Hard and Soft Palates.- 11. Teeth.- II. Toluidine Blue as a Screening Detection Method.- III. Oral Cytology as a Screening Detection Method.- References.- 3. Diagnosis.- I. Epidermoid Carcinoma.- 1. Carcinoma of the Lip.- 2. Carcinoma of the Tongue.- 3. Carcinoma of the Floor of the Mouth.- 4. Carcinoma of the Alveolar Mucosa and Gingiva.- 5. Carcinoma of the Palate.- 6. Carcinoma of the Buccal Mucosa.- 7. Verrucous Carcinoma.- 8. Histopathology.- 9. Metastasis.- II. Carcinoma-in-situ.- III. Basal Cell Carcinoma.- IV. Malignant Melanoma.- V. Odontogenic Tumors.- 1. Ectodermal Origin.- 2. Mesodermal Origin.- 3. Mixed Origin.- VI. Fibro-Osseous Lesions.- 1. Fibro-Osseous Jaw Lesions of Periodontal Membrane Origin.- 2. Fibro-Osseous Jaw Lesions of Medullary Bone Origin.- 3. Malignant Fibro-Osseous Lesions of the Jaws.- VII. Salivary Gland Tumors.- 1. Benign Tumors.- 2. Malignant Tumors.- VIII. Biopsy.- 1. Incision Biopsy Procedure.- 2. Punch Biopsy Procedure.- 3. Excision Biopsy Procedure.- References.- 4. Pretreatment Evaluation.- I. Medical History and Symptoms.- II. Evaluation of Extent of Disease.- III. Consultations.- IV. Pretreatment Management.- V. Informed Consent.- VI. Non-Standard Treatment.- VII. Rules for Classification.- VIII. TNM Classification.- 1. Primary Tumor (T).- 2. Nodal Involvement (N).- 3. Distant Metastasis (M).- IX. Postsurgical Treatment Residual Tumor (R).- X. Summary of Stage Groupings.- XI. Common Departures from Sound Management.- 1. Open Biopsy of a Lump in the Neck Before Performing a Complete Head and Neck General Examination.- 2. Inadequate Incisional Biopsy of an Oral Cavity Lesion.- 3. Inadequate Excisional Biopsy of a Suspicious Oral Cavity Lesion.- 4. Failure to Review Previous Histopathologic Slides.- 5. Permitting a Single Histopathologic Benign Diagnosis to Override a Clinical Diagnosis of Carcinoma.- 6. Biopsies of the Larynx, Hypopharynx, Nasopharynx, Esophagus, or Trachea Prior to Radiologic Studies.- 7. Lack of Multidisciplinary Approach Where Indicated.- 8. Tailoring the Scope of Surgical Resection to the Ability of the Surgeon Rather than to the Objective Requirements Imposed by the Lesion.- 9. A Compromise of the Ablative Phase of Surgery in Order to Accommodate Limited Reconstructive Skills.- 10. Compromise of Surgical Margins Because Radiation Therapy or Chemotherapy Was or Is To Be Given.- 11. Performing the Right Operation on the Wrong Patient.- 12. Assessing the Degree of Success or Failure of Radiation Therapy on the Basis of the Response of the Lesion During or Immediately on the Completion of Treatment.- 13. Failure to Realize the Implication of the "Condemned Mucosa" or Multiple Primary Syndrome.- 14. Failure to Perform a Complete General Physical Examination As Well As a Complete Head and Neck Examination.- 15. Prolonged Watch-and-Wait Attitude in the Face of an Asymptomatic Mass.- 16. Inadequate Search for an Occult Primary.- 17. Abandonment of the Patient with Neck Metastasis from an Undetectable Primary.- 18. Enucleation of Tumors of the Major Salivary Glands and Thyroid Gland.- 19. Treating a Patient with Antibiotics for an Extended Period of Time Without a Biopsy.- References.- 5. Treatment.- I. Surgical Treatment of Head and Neck Cancer. Donald P. Shedd.- 1. Oral Cavity Cancer.- 2. Pharyngeal Cancer.- 3. Laryngeal Cancer.- 4. Paranasal Sinus Cancer.- 5. Salivary Gland Cancer.- 6. Radical Neck Dissection.- References.- II. Radiation Therapy in the Management of Head and Neck Tumors. Luther W. Brady and Lawrence W. Davis.- 1. General Considerations.- 2. The Role of Radiation Therapy in Head and Neck Sites.- 3. Treatment of Neck Nodes.- 4. Late Effects of Radiation Therapy.- 5. Future Approaches.- References.- III. Chemotherapy. James E. Hamner, III.- 1. General Remarks.- 2. Combined Treatment Modalities.- References.- 6. Follow-Up.- General Considerations.- References.- 7. Rehabilitation.- I. General Principles of Rehabilitation. James E. Hamner, III.- II. Maxillofacial Prosthetics. Joe B. Drane.- References.- 8. Series of Case Examples.- 1. Case No. 1 : Squamous Cell Carcinoma.- 2. Case No. 2: Squamous Cell Carcinoma.- 3. Case No. 3: Cemento-Ossifying Fibroma.- 4. Case No. 4: Osteosarcoma.- 5. Case No. 5: Cherubism.