عنوان

Genetic Models of Immune and Inflammatory Diseases

(Number (ISBN

1461223768

(Number (ISBN

9781461223764

Number

b546214

Title Proper

Genetic Models of Immune and Inflammatory Diseases

General Material Designation

[Book]

First Statement of Responsibility

edited by Abul K. Abbas, Richard A. Flavell.

Place of Publication, Distribution, etc.

New York, NY

Name of Publisher, Distributor, etc.

Springer New York

Date of Publication, Distribution, etc.

1996

Specific Material Designation and Extent of Item

(xvi, 177 pages 20 illustrations)

Series Title

Serono Symposia USA.

Text of Note

I. Autoimmunity --;1. Intensification of Diabetes in B7-1 Transgenic Mice --;2. A Transgenic Window on Self-Reactive T Lymphocytes --;3. Induction and Breaking of Peripheral Tolerance --;4. T-Cell Development and Tolerance in Virus-Specific Transgenic Models --;5. Inflammatory Disease in HLA-B27 Transgenic Rats --;II. Autoimmunity, Infections --;6. The Role of CD40 Ligand in Regulation of Immune Response --;7. Adventures in Antigen Presentation --;8. The Effect of MHC Encoding Transgenes on IDDM in NOD Mice --;9. The Immunology of Leishmania Major Infection in Mice --;III. Cytokines, Co-Stimulators, Tumor Immunity --;10. The Regulatory Functions of Co-Stimulators Revealed in Transgenic Mice --;11. B7-Deficient Mice Reveal an Alternative Functional CTLA-4 Counterreceptor --;12. Cytokine Transgenic Mice and Autoimmunity --;13. Gaining Insights into the Ontogeny and Activation of T Cells Through the Use of Gene-Targeted Mutant Mice --;14. B7-Mediated Co-Stimulation of T Cells: CTLA-4 Can Deliver Inhibitory Signals --;IV. Cytokine Deletions --;15. Lymphoid Organogenesis and Inflammation Are Mediated by Lymphotoxin --;16. The Role of Interferon-? in the Development of Type I Diabetes --;17. Cytokine-Deficient Mouse Mutants --;Author Index.

Text of Note

Immunomodulatory agents have been expressed in defined tissues or throughout the body, providing tools for studying the functional consequences of dysregulated expression of biologi- cal response modifiers.

Human genetics.

Immunology.

Medicine.

Class number

Book number

edited by Abul K. Abbas, Richard A. Flavell.

Abul K Abbas

R A Flavell

Electronic name

[Book]

Y